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Showing 1 to 20 of 8488 for “"MSC"”.

  1. MSC DERIVED EV IN REGENERATIVE MEDICINE

    Hotham, WilliamUniversity of Cambridge2022

    … healthy states. Mesenchymal stem/stromal cells (MSC) are thought to facilitate tissue repair via either progenitor or secreaome functions. BM-MSC have, in previous work, been investigated as a therapy for OA via either their direct application or through their secreted Extracellular Vesicles …

    cambridge Repository record

  2. Mindful self-compassion (MSC) as an intervention for infertility related distress: A pilot self-help version of MSC

    Halleran, Maria GraceFaculty of Graduate Studies and Research, University of Regina2022

    … related distress. Mindful Self-Compassion (MSC) is a relatively novel treatment that involves learning mindfulness techniques with an explicit focus on self-compassion. Previous literature has indicated that women report lower levels of self-compassion than men. Increased levels of …

    regina Repository record

  3. Generation of SDL specifications from UML and MSC use cases

    Bourduas, Stephan2001

    concordia Repository record

  4. Optimization and Translation of MSC-Based Hyaluronic Acid Hydrogels for Cartilage Repair

    Erickson, Isaac E2011

    … into the potential of mesenchymal stem cells (MSCs) as an alternative cell source. MSCs are multipotent cells that can differentiate towards a chondrocyte phenotype in a number of biomaterials, but no combination has successfully recapitulated the native mechanical function of healthy articular …

    penn Repository record

  5. Investigation into the Utility of the MSC ADAMS Dynamic Software for SimulatingRobots and Mechanisms

    Xue, XiaoOhio University2013

    … manipulator are modeled and simulated in MSC ADAMS/View. Forward dynamics simulation is done on the Stewart-Gough parallel manipulator; Inverse dynamics simulation is done on Slider-Crank mechanism, 2R planar serial robot and 4-bar mechanism. In forward dynamics simulation, the forces are …

    ohiolink Repository record

  6. Enhancement of spatially-controlled MSC responses in a multi-compartment CG scaffold for tendon-bone junction regeneration

    Grier, William KaneUniversity of Illinois at Urbana-Champaign2018

    There have been many advancements in the field of tissue engineering for the repair or regeneration of single tissues. However, orthopedic injuries often occur at the interface between soft tissues and bone. The tendon-bone junction (TBJ) is a classic example of such an interface, containing …

    uiuc Repository record

  7. MICRO-CT EVALUATION OF MSC/HUVEC/HSC-MEDIATED ANGIOGENESIS IN LARGE PCL-ßTCP CONSTRUCTS IMPLANTED IN NUDE MICE

    Stosich, Michael StevenTemple University. Libraries2011

    … were seeded with human mesenchymal stem cells (MSCs) plus HUVECs or HSCs. Groups (N=12) consisted of scaffold samples seeded with MSCs alone, MSCs and HUVECs, MSCs and HSCs, and no cells. Cell suspension containing thrombin was evenly seeded into the micro porous constructs, sealed with …

    temple Repository record

  8. Ersatz von fötalem Kälberserum (FCS) im Standardmedium von mesenchymalen Stromazellen (MSC) durch Thrombozytenlysat - Herstellung und Identifizierung wachstumsfördernden Faktoren

    Maurer, CarolineUniversität Ulm

    ulm-diss Repository record

  9. SASSI and the MSC: How effective have they been with reaching consumers in Cape Town and raising their awareness

    Landey, DavidDepartment of Oceanography2013

    … such campaigns: the Marine Stewardship Council (MSC) and the Southern African Sustainable Seafood Initiative (SASSI). This study aimed to investigate the awareness of consumers at major retail outlets in Cape Town of these initiatives, and to link awareness with seafood consumption behaviour. It …

    cape-town Repository record

  10. May I Be Kind to Myself : A Pilot Study on the Experience of a 6-Week Short Course in Mindful Self-Compassion (SC-MSC)

    Spicer, KaylaUniversité d'Ottawa / University of Ottawa2023

    … Short Course in Mindful Self-Compassion (SC-MSC). Five women completed the course as well as a semi-structured interview with a targeted set of questions pertaining to uncovering their lived experiences. Thematic analysis was used to construct detailed accounts of each participants' …

    ottawa-retro Repository record

  11. Investigating the efficacy and mechanism of action of mesenchymal stromal cell therapy in burn wound healing

    Whelan, Derek S.University College Cork2017

    … studies suggest that mesenchymal stromal cell (MSC) therapy may be efficacious in accelerating wound healing. Which source of MSC is therapeutically superior has not been well established, especially in large clinically relevant animal models. We therefore investigated the efficacy of Bone …

    cork Repository record

  12. Investigation of efficacy and mechanisms of action in mesenchymal stromal cell therapy for chronic lung diseases

    Kennelly, HelenNational University of Ireland Maynooth2015

    Mesenchymal Stromal Cells (MSC) are adult multipotent cells that possess self-­‐renewal and regenerative capacities, with the ability to differentiate into a variety of cell types. They have potent immunosuppressive abilities, facilitating the use of allogeneic MSC as a cellular therapy. …

    maynooth Repository record

  13. The multiple migratory mechanisms of systemically infused mesenchymal stem cells to sites of inflammation

    Teo, Grace Sock LengMassachusetts Institute of Technology2014

    Systemically infused mesenchymal stem cells (MSC) are being explored for their immunomodulatory therapeutic potential in multiple inflammatory pathologies. This therapeutic potential has been associated with the ability of MSC to accumulate at sites of inflammation following infusion. However, …

    mit Repository record

  14. Ruolo delle cellule staminali mesenchimali in modelli cellulari e animali di nefropatia

    Magnasco, Alberto <1964>Alma Mater Studiorum - Università di Bologna2008

    Background. Mesenchymal stem cells (MSC) may be of value in regeneration of renal tissue after damage, however lack of biological knowledge and variability of results in animal models limit their utilization. Methods. We studied the effects of MSC on podocytes ‘in vitro’ and ‘in vivo’ utilizing …

    bologna Repository record

  15. A Delineation of Mesenchymal Stromal Cell Therapeutic Action in New Models of Acute and Chronic Graft versus Host Disease

    Healy, Marc E.National University of Ireland Maynooth2015

    … capacity of mesenchymal stromal cells (MSC) has been extensively characterised in terms of T cells, natural killer cells and dendritic cells suppression; however the ability of MSC to modulate B cell biology is not fully understood. This immune suppressive ability has led to the …

    maynooth Repository record

  16. An Investigation of The Effect of Hypoxic Culture on Mesenchymal Stromal Cell Immunomodulation and Biodistribution in-vivo

    Cahill, Laura A.National University of Ireland Maynooth2016

    … of hypoxic culture on mesenchymal stromal cell (MSC) immunomodulation and biodistribution in-vitro and in-vivo. Thus far, MSC have proved therapeutically beneficial for a number of inflammatory diseases such as acute Graft versus Host Disease (aGvHD). However, despite extensive in-vitro …

    maynooth Repository record

  17. Immune Mechanisms of Mesenchymal Stem Cell Therapy for Acute Graft versus Host Disease

    Tobin, Laura M.National University of Ireland Maynooth2012

    … investigate the role of Mesenchymal stem cells (MSC) in the modulation of immune responses, focusing on suppression and induction of immune tolerance. To date, MSC therapy has proved beneficial for the treatment of inflammatory and autoimmune diseases, such as acute Graft versus Host Disease …

    maynooth Repository record

  18. Mesenchymal stem cell therapy for the treatment of myocardial infarction

    Gleeson, BirgittaUniversity College Cork2014

    Mesenchymal stem cells (MSCs) are currently under investigation as repair agents in the preservation of cardiac function following myocardial infarction (MI). However concerns have emerged regarding the safety of acute intracoronary (IC) MSC delivery specifically related to mortality, …

    cork Repository record

  19. Inflammatory and Immune Effects of Intra-Articular Mesenchymal Stem Cells in Horses

    Pigott, John H.The Ohio State University2013

    … bone marrow-derived mesenchymal stem cells (MSC) in horses. The study group consisted of 6 five-year-old Thoroughbred mares, free of musculoskeletal disease in the fetlocks. The 4 fetlock joints were injected on day 0 with 15 million MSC from the described MSC groups and were assessed for 28 …

    ohiolink Repository record

  20. Lung microenvironment plays a key role on the protective vs. detrimental effects of mesenchymal stromal cell therapy in acute lung injury

    Islam, Diana2017

    … pulmonary fibrosis. Mesenchymal stromal cells (MSC) are considered good candidates for therapy due to their ability to home into injury sites and help in recovery. However, MSC are sensitive to stimulations from their surroundings and some evidence suggests that MSCs can contribute to fibrosis. …

    toronto-retro Repository record

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