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Showing 1 to 1 of 1 for “"MRTX1133"”.
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Functional contribution of epithelial to mesenchymal transition program on KRASG12D targeting efficacy in pancreatic cancer
… Sotorasib, paved the way for the development of MRTX1133, a KRAS<sup>G12D </sup>inhibitor. Although MRTX1133 improved survival outcomes in pre-clinical resistance to KRAS<sup>G12D</sup> inhibition develops after prolonged treatment. As such, one of the main investigative avenues towards …