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Showing 1 to 3 of 3 for “"MRR1"”.
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Asymptotic Results for Model Robust Regression
… proposed the Model Robust Regression estimate (MRR1) in which estimates of the parametric function, ƒ, and the nonparametric function, 𝑔, were combined in a straightforward fashion via the use of a mixing parameter, λ. This technique was studied extensively at small samples and was shown to be …
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Transcriptional Regulation of Azole Antifungal Resistance in Candida albicans
… zinc cluster transcription factor, designated as MRR1 (multidrug resistance regulator), that was coordinately up-regulated with MDR1 in drug-resistant clinical C. albicans isolates. The disruption of MRR1 in two resistant clinical isolates abrogated MDR1 expression and multidrug resistance. MRR1 …
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Investigation of Clinically Relevant Fluconazole Resistance Mechanisms in the Fungal Pathogen Candida parapsilosis
… albicans. Gain-of-function polymorphisms in MRR1 and TAC1 have been shown to elevate the expression of MDR1 and CDR1/CDR2 respectively and directly contribute to fluconazole resistance in Candida albicans. Our lab previously identified three resistant isolates with upregulated CpMDR1 …