Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 86 for “"MRI contrast"”.
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Fluorinated Metal Complexes as MRI Contrast Agents
Magnetic resonance imaging (MRI) is a vital tool in today’s modern healthcare system. MRI is preferred over positron emission tomography (PET) and X-ray computed tomography (CT) because it is non-invasive, non-radioactive, and provides 3-D imaging directly in vivo. Contrast agents are used in order …
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Lanthanide Functionalised gold nanoparticles as MRI contrast agents
… synthesize and characterise nanoparticle-based MRI contrast agents. In the first instance, the DTPA (diethylenetriaminepentaacetic acid) based ligand was designed, synthesized and characterised. This ligand was utilised for stabilisation of gold nanoparticles. The gold nanoparticles protected by …
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Electronic Relaxation Properties of Gadolinium Based MRI Contrast Agents
Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs
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Engineering genetically-encodable MRI contrast agents for in vivo imaging
Magnetic resonance imaging (MRI) is gaining recognition as a powerful tool in biological research, offering non-invasive access to anatomy and activity at high spatial and temporal resolution. However, the range of biological phenomena accessible to measurement by MRI is limited, due to a current …
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The design, syntheses, and physico-chemical studies of MRI contrast agents
Magnetic Resonance Imaging (MRI) is a popular and powerful clinical diagnostic tool. The development of MRI contrast agents allows for even greater diagnostic ability. This thesis will address the design, syntheses and physico-chemical studies of two specific classes of MRI contrast agents: the …
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Novel MRI Contrast Agents Based on Functional DNA and Nanomaterial Conjugates for Biomedical Applications
Finally, we have demonstrated that the fluorescein encapsulated one micron liposomes can be used to detect inorganic mercury in water. At the same time, we have shown that chelators of inorganic mercury can be encapsulated in liposomes and released upon mercury detection.
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Advanced design and experimental validation of MRI contrast agents for fluid pressure mapping using microbubbles
… pressure using Magnetic Resonance Imaging or MRI and includes numerical simulations and experimental MRI. The nature of this study is such that techniques other than MRI have been extensively used to assess the contrast agent for its physical behaviour. These techniques include rheometry, …
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Polymer-mediated assembly of MRI contrast agents and their use in imaging of vascular defects
… worldwide. As magnetic resonance imaging (MRI) provides the highest spatial resolution and best soft tissue contrast among common imaging techniques, it remains an appealing approach to vascular imaging. MRI, however, has relatively low sensitivity to its contrast agents compared to other …
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EPR of powders, crystals, and clays of MRI contrast agents: zero field splitting and proton relaxation
MRI (magnetic resonance imaging) has brought great advances to diagnostic medicine, especially with the use of contrast agent (CA’s) for comparison of images with and without contrast. Since the first use of Gd III CA’s in imaging in the early 1980’s, the chemistry and physics of these CA’s have …
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Investigation of a Potential Macromolecular MRI Contrast Agent Prepared From PPI (G = 2, Polypropyleneimine, Generation 2) Dendrimer Bifunctional Chelates
… imaging of this complex resulted in a 52% contrast enhancement in the rat kidney following the agents' administration in vivo.
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ELECTROCHEMICAL METHODS FOR THE SUSTAINABLE RECOVERY OF GADOLINIUM FROM MRI CONTRAST AGENTS AND FOR THE FABRICATION OF GADOLINIUM-RICH NANOPARTICLES.
The widespread use of gadolinium-based contrast agents (GBCAs) in magnetic resonance imaging (MRI) has led to increasing concern over the release of gadolinium into the environment. Gadolinium (Gd) is excreted in complexed forms that are stable and difficult to remove through conventional …
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Fundamental studies and applications for the development of novel MRI contrast agents: Hyperpolarized xenon-129 and superparamagnetic iron oxide nanoparticles
… human body by use of magnetic resonance imaging (MRI). Indeed, MRI is perhaps the most well-known application of MR, and in the clinic, MRI is growing in popularity as an alternative to other imaging modalities such as computerized tomography (CT), positron emission tomography (PET), and x-ray, …
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The Development of a Novel Tumor -Specific MRI Contrast Agent Targeting the High Affinity Folate Receptor: In Vitro and in Vivo Specificity, Toxicity, and Biodistribution
The need to develop target-specific MRI contrast agents to aid in disease characterization remains highly essential. Here, we present a generation four polyamidoamine (PAMAM) dendrimer conjugated to folic acid that specifically targets the high affinity folate receptor (hFR) overexpressed on more …
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