Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"MRC Laboratory for Molecular and Cell Biology"”.
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Nitric oxide induces chromatin remodelling in the developing central nervous system
… least in part, by the overproduction of neurons and the survival of a select few that compete for limited survival and growth promoting factors, such as neurotrophic factors. The neurotrophin brain-derived neurotrophin factor (BDNF) has been shown to play an important role in proliferation and …
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The role of anchorage in cell cycle control
Mammalian cells generally require both mitogens and anchorage signals in order to proliferate. Failure to receive these signals results in either cell-cycle arrest or cell death, known as anoikis, due to activation of anchorage-dependent checkpoint mechanisms. Transformed cells alleviate these …
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The identification of the Tao-1 kinase as a key regulator of microtubule dynamics
In a multicellular animal, the different functions of cells are dependent on their diversity of shapes. Protein phosphorylation and dephosphorylation play an important role in altering the cell shape in response to internal and external signals. In this study I focused on all kinases to explore the …