Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"MR Spectroscopy"”.
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Neuropsychological Outcome following Perinatal HIE: Utility of MR Spectroscopy
… variance in outcome. The prognostic utility of MR Spectroscopy in the pathogenesis of asphyxia is promising (Wyatt, 1994). Innovative research indicates that MR Spectroscopy can accurately predict outcome at one year in 91% of neonates with central nervous system injuries (Holshouser et al., …
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MR Spectroscopy and SWI: Neuropsyehological Outcome after Pediatric Brain Injury
… acute single and multi-voxel Magnetic Resonance Spectroscopy (MRS) and Susceptibility Weighted Imaging (SWI) when predicting long-term neurocognitive functioning in pediatric TBI patients. Twenty children/adolescents (mean age 13.3 years, 5.8 SD) treated at Loma Linda University Children's …
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Usefulness of MR Spectroscopy in Differential Diagnosis of Cognitive Dysfunction
"서론: 인지기능 장애의 조기진단과 치료에 대한 관심이 높아지면서 알쯔하이머병, 경도인지장애, 주관적인 기억장애 등의 감별진단을 위한 많은 영상의학적 진단 방법들이 개발되고 있으며 그 중 자기공명분광영상은 비침습적으로 병태생리학적 기전을 연구할 수 있어 널리 이용되고 있다. 본 연구에서는 인지기능 장애 환자들에게서 자기공명분광영상을 시행하여 각 질환간의 차이와 각 영역별 인지 장애 정도와의 상관성을 알아보고자 하였다. 연구대상 및 방법: 2008년 7월부터 9월까지 아주대학교병원 신경과 치매 클리닉에 내원한 환자 중 …
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Real-time motion and main magnetic field correction in MR spectroscopy using an EPI volumetric navigator
… do not lie still during Magnetic Resonance Spectroscopy (MRS) scans, real-time volume of interest (VOI), frequency, and main magnetic field (B0) shim correction may be necessary. This work demonstrates firstly that head movement causes significant B0 disruption in both single voxel …
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IMAGING SPECIFIC ABSORPTION RATE WITH MR THERMOMETRY USING PARAMAGNETIC LANTHANIDE COMPLEXES AND IN VIVO GABA MR SPECTROSCOPY IN MOVEMENT DISORDERS
Magnetic Resonance Imaging (MRI) is a popular imaging modality due to its ability to provide excellent soft tissue contrast without exposure to ionizing radiation. It can be used for temperature monitoring (thermometry) as well as for assessing the biochemistry in vivo (MRS). This dissertation …
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Human brain functional dynamic connectivity: challenges and potentials in health and disease studies
… When derived from restingstate functional MRI (rs-fMRI), dynamic or time-varying connectivity (TVC) estimates result from temporal fluctuation correlations of BOLD fMRI time series between brain regions. However, given the novelty of this research line, there are still various challenges …
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Skeletal Muscle Energetics and Mechanics: The Effects of Magnesium on Resting and Contracting Muscle as Studied by Phosphorus Magnetic Resonance Spectroscopy
… skeletal muscle energetics and mechanics using MR spectroscopy (MRS) with particular reference to the role of magnesium. The accuracy and precision of $\sp{31}$P MRS as a technique for this study was evaluated. A servocontrol system was implemented such that isolated frog skeletal muscles could …
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Quantitative lactate-specific magnetic resonance imaging and proton spectroscopy of muscle and brain
The techniques of magnetic resonance (MR) imaging and spectroscopy have recently garnered much attention as tools for detecting and localizing metabolic changes in living tissues in various pathologic states and during physiologic activation. For example, in studies employing localized MR …
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Ultrahigh Field Magnetic Resonance Imaging – Technical Development and Translational Applications
<p>Magnetic resonance imaging (MRI) may be used to provide detailed images of the human body with excellent soft tissue contrast. Alongside its current widespread clinical applications for diagnosis and treatment, MRI allows researchers to measure structure and function of different tissue types in …
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Energy failure following traumatic brain injury: Potential mechanisms and impact of normobaric hyperoxia
… diffusion tensor imaging and whole-brain proton MR spectroscopy (WB 1H MRS) as imaging biomarkers to investigate normobaric hyperoxia as a therapeutic option following traumatic brain injury (TBI). Using ([18F] FMISO PET evidence of tissue hypoxia consistent with microvascular ischaemia was found …
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Simultaneous multislice spiral and EPI chemical shift imaging
… excitation methods of 3D slabs used for MR Spectroscopy Imaging (MRSI) include long dead times in each TR. This dead time is necessary for magnetization moments' longitudinal relaxation, and so a good SNR efficiency. The fact that SNR is one of the dominant challenges that MRSI faces …
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Distinct Neuropsychological Profile and Associated Neurochemical Changes in Individuals with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS)
… visually-mediated and verbally-mediated tasks. MR Spectroscopy (NAA, Lactate), Chi-square, t-tests, Pearson correlations, ANOVA, and Generalized Estimating Equations were run (α=0.05).</p> <p>Results:<strong> </strong>When compared to carriers and controls, MELAS patients had: 1) most impaired …
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Towards high-resolution magnetic resonance spectroscopic imaging: spatiotemporal denoising and echo-time selection
Magnetic resonance spectroscopic imaging (MRSI) enables acquisition of spatial-spectral nuclear spin distributions. Compared to conventional MRI, the additional spectral information provides a powerful tool for in vivo study of biological tissues. However, considerable practical challenges, which …
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Development of Optimised Pulse Sequences for Magnetic Resonance Imaging of Tumour Metabolism
… of tissue metabolism in vivo using 13C MRSI. The principal limitation of the technique is the short lifetime of the hyperpolarisation, which requires the use of very fast imaging methods. As well as being fast the imaging pulse sequence must make economical use of the polarisation since …
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On Nature of the Gradient Echo MR Signal and Its Application to Monitoring Multiple Sclerosis
… a non-invasive tool, Magnetic resonance imaging: MRI) plays a key role in MS diagnosis. Numerous MRI techniques have been proposed over the years. Among most widely used are conventional T1-weighted: T1W), T2-weighted: T2W) and FLuid Attenuated Inversion Recovery: FLAIR) imaging techniques. …
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Fiber Orientation Modeling: a Method to Improve Quantitation of Intramyocellular Lipids in Human Subjects at 7 Tesla
… As a noninvasive method of estimating IMCL, 1H MR spectroscopy of muscle fat has been a popular method for measuring the concentration of IMCLs, a goal highly desirable for research in the pathogenesis of type 2 diabetes. Extramyocellular lipids (EMCL) are often considered to be deposited along …
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Implementation of Hadamard Encoding and Reconstruction of MEGA-Edited Spectroscopy (HERMES) for quantification of ɣ-aminobutyric acid (GABA) and glutathione (GSH)
… in the brain, are challenging to detect using MR spectroscopy due to the fact that their resonance frequencies overlap with those of other more abundant metabolites. The advanced spectral editing techniques involving J-difference editing that are required to resolve the overlapping signals of …
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Quantitative 31P-MR-spektroskopische Untersuchung globaler Herzerkrankungen unterschiedlicher Genese - Verlaufsbeobachtung nach Aortenklappenersatz und unter Therapie bei Dilatativer Kardiomyopathie
… dass mit Hilfe der quantitativen 31P-MR-Spektroskopie der Energiemetabolismus des Myokards beurteilt werden kann. Mit der gewählten Methode SLOOP ist nun auch eine Bestimmung der absoluten Konzentration der energiereichen Phosphate PCr und ATP möglich; im Gegensatz dazu wurde bisher …
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The neurocognitive mechanisms of perceptual inference in autism
… from non-social perception task-based functional MRI studies examining differences between autistic and typical participants. Overall, autistic people, compared to typical controls, showed less activity in the prefrontal cortex during perception tasks. More refined analyses revealed that, when …
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Single-Voxel- versus Multi-Voxel-Protonen-MR-Spektroskopie bei verschiedenen intrakraniellen Läsionen
… Läsionen mittels Singelvoxel- versus Multivoxel-MR-Protonen-Spektroskopie signifikant unterschiedliche Ergebnisse bestehen. Untersucht wurden Hirntumoren der WHO-Grade 2 bis 4, Metastasen und fokal-entzündliche Läsionen. Zusammenfassend ist die Unterscheidung zwischen normalem und pathologisch …
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