Global ETD Search
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Showing 1 to 3 of 3 for “"MPS IIIB"”.
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Development of Quantitative Tools for the Characterization and Analysis of the Blood Brain Barrier in Normal and MPS IIIB Mice
… as the metabolic disease Mucopolysaccharidosis IIIB, have been shown to cause breaches in the BBB’s integrity, thus suggesting a possible mechanism to administer treatment around this restriction could be to utilize a specific disease’s own pathology. In order to understand the extent of BBB …
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Neuropathologic characterization of a canine model of mucopolysaccharidosis IIIB and additional studies in anti-inflammatory therapy and neuroinflammatory kinetics
<p>The mucopolysaccharidoses (MPSs) are a heterogenous group of lysosomal storage diseases that are designated MPS I through MPS IX (excluding MPS V and MPS VIII) that result in deficiencies in specific lysosomal enzymes that are responsible for the stepwise degradation of glycosaminoglycans …
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Improving CNS Delivery of Genistein for the Treatment of Sanfilippo Syndrome
… syndrome or mucopolysaccharidosis type III (MPS III), a type of lysosomal storage disease, is a rare genetic disorder inherited in an autosomal recessive manner. Individuals affected by this disease lack the ability to produce one of the four enzymes responsible for the lysosomal degradation …