Global ETD Search
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Showing 1 to 7 of 7 for “"MPCC"”.
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Engineering complex liver models for drug screening and infectious diseases: a biomaterials and co-culture perspective
… and drug screening. Micropatterned cocultures (MPCCs) of primary human hepatocytes (PHHs) and supportive stromal cells have been shown to display high hepatic functions for long-term drug and disease studies. However, MPCCs lack liver non-parenchymal cells (NPCs) and the proper …
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Forward and inverse American option pricing via a complementarity approach
… program with complementarity constraints (MPCC). Two methods for solving MPCCs, an implicit programming algorithm (IMPA) and a new hybrid algorithm, are studied in this dissertation. We test both algorithms and report their numerical performance for solving MPCCs derived under the Dupire …
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Autonomous Racing and Overtaking for the Voyager Unmanned Ground Vehicle
… of a model predictive contouring control (MPCC) system for a differential-drive unmanned ground vehicle (UGV) to perform autonomous racing and dynamic obstacle avoidance. Two obstacle-avoidance formulations are evaluated separately under matched scenarios: (i) a cost-function (soft) penalty …
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Engineering in vitro models of non-alcoholic fatty liver disease
… Here we show that micropatterned co-cultures (MPCCs) of PHHs and stromal cells maintain glucose and lipid metabolism in hepatocytes, which suggests their utility for in vitro disease models of NAFLD. Major advances in culturing methods were developed to increase the insulin sensitivity and …
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Design of genetic regulatory networks
… programs with complementarity constraints (MPCCs). Since genetic regulatory networks are dynamic systems, DT is an appropriate optimization strategy, and is used to determine optimal network parameter values. An MPCC formulation is introduced that supports network structure optimization. The …
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Constraint qualifications and stationarity concepts for mathematical programs with equilibrium constraints
An exhaustive discussion of constraint qualifications (CQ) and stationarity concepts for mathematical programs with equilibrium constraints (MPEC) is presented. It is demonstrated that all but the weakest CQ, Guignard CQ, are too strong for a discussion of MPECs. Therefore, MPEC variants of all the …
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Global solution to parametric complementarity constrained programs and applications in optimal parameter selection
… program with complementarity constraints (MPCC), which is also referred to as the mathematical program with equilibrium constraints (MPEC) interchangeably in the chapter. We review the philosophy and main techniques behind the existing algorithms developed for solving MPEC. This background …