Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 13 of 13 for “"MODY"”.
-
Genetic and Molecular Analysis of Islet-and Liver-Enriched Transcription Factors in Metabolism and Development
<p>Maturity-onset diabetes of the young (MODY) are monogenic forms of type 2 diabetes that are characterized by an early disease-onset, autosomal dominant inheritance, and defects in insulin secretion. Genetic studies have identified mutations in at least six genes associated with different forms …
-
Monogenic diabetes in large population settings
… main sections. The first two sections discuss MODY and lipodystrophy, respectively, and describe the varying phenotypes, diagnosis, treatment, and genetic causes of these diseases. The final section provides an overview of how large population cohorts can be used to study rare diseases and the …
-
Exploring the Grey Zone between Type 1 and Type 2 Diabetes
… gene. Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes inherited in an autosomal dominant fashion (individual has one copy of a mutant gene and one normal gene on a pair of autosomal chromosomes) characterized by nonketotic diabetes, age at onset before 25 years and …
-
Genetic and Metabolic Markers for the Development of Diabetes after Gestational Diabetes Mellitus
… offered to all pregnant women. The prevalence of MODY mutations among women with GDM and a family history of diabetes was found to be 5%. Arabian women were more insulin resistant than Scandinavian women with the same BMI, and showed impaired beta cell compensation for their degree of insulin …
-
Patterns of arthropod distribution and determinants of arthropod assemblage composition in a natural West African savannah
This study investigated patterns of arthropod community organisation and the processes structuring these communities on a range of different tree species in a natural West African savannah (Comoé National Park, Côte d'Ivoire). It described and analysed patterns of arthropod distribution on the …
-
Improving the risk identification process for a global supply chain
This thesis describes a proposed risk identification process that is intended to systematically identify potential risks that could materialize within a company's supply chain that would affect component supply. The process is based on a specific situation at Nokia though is intended to extend to …
-
Genetic and immunological risk factors of gestational diabetes mellitus
… we studied whether common variants in MODY [Glucokinase (GCK), hepatocyte nuclear factor 1-alpha (HNF1A), and HNF4A] genes also increase the risk of GDM. We found that the A-allele of the ?30G>A polymorphism in the beta-cell-specific promoter of the GCK increases the risk of GDM with a …
-
Supporting Transparent Distributed Messaging for Dataflow Applications in Power Electronics Control Systems
This thesis presents the design and implementation of a transparent messaging protocol for distributed communication between processors. The processors are designed using dataflow architecture. The protocol ensures transparent asynchronous communication between distributed processes. The protocol …
-
Track angle error (TAE) displays and their effect on pilot perforamnce during instrument approaches
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 1997.
-
Impact of Liquefied Natural Gas usage and payload size on Hybrid Wing Body aircraft fuel efficiency
This work assessed Hybrid Wing Body (HWB) aircraft in the context of Liquefied Natural Gas (LNG) fuel usage and payload/range scalability at three scales: H1 (B737), H2 (B787) and H3 (B777). The aircraft were optimized for reduced fuel burn and airframe noise at approach, based on NASA N+3 goals …