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Showing 1 to 2 of 2 for “"MMTV-Neu mice"”.

  1. p,p' DDE Regulated Gene Expression and Possible Mechanisms of Action in Breast Tumor

    … had inconsistent findings, however a study in MMTV-neu mice determined that localized, developmental exposure to the reported anti-androgen p,p' DDE accelerated mammary tumor development. This study tested the potential cancer-promoting actions of p,p' DDE, the most prevalent and persistent DDT …

    duquesne Repository record for p,p' DDE Regulated Gene Expression and Possible Mechanisms of Action in Breast Tumor (opens in a new tab)

  2. The Addition of Melatonin to 17beta-Estradiol and Progesterone Modulated Markers Relevant to Mammary Tumor Development and Modulated Steroid Receptors Relevant to Uterine Protection in a Mouse Model of Breast Cancer

    … non-ovariectomized, 60-day old female MMTV/unactivated Neu mice were provided therapies comprised of E2 and P4, with or without nocturnal melatonin supplementation, given continually for 30 days. To investigate actions on mammary tissues, whole mount, microarray, and real-time RT-PCR …

    duquesne Repository record for The Addition of Melatonin to 17beta-Estradiol and Progesterone Modulated Markers Relevant to Mammary Tumor Development and Modulated Steroid Receptors Relevant to Uterine Protection in a Mouse Model of Breast Cancer (opens in a new tab)