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Showing 1 to 20 of 95 for “"MMP-2"”.

  1. Imagerie moléculaire de la MMP-2

    Lebel, RéjeanUniversité de Sherbrooke2012

    Les métalloprotéinases de matrice (MMPs) sont des enzymes impliquées dans la restructuration tissulaire et la migration cellulaire. La MMP-2, en particulier, a été reconnue comme biomarqueur de la progression ou du pronostic de plusieurs pathologies, comme l'arthrite, l'athérosclérose, l'infarctus …

    sherbrooke Repository record

  2. Die Expression der Matrix-Metalloproteinasen MMP-2 und MMP-9 beim Kolon- und Rektumkarzinom

    Arndt, MarliesPublikationsserver der RWTH Aachen University2005

    … carcinoma, the matrix-metalloproteinases MMP-2 and MMP-9 play a special role. In this study we investigated the expression of MMP-2 and MMP-9 and their importance for therapy and prognosis of colon- and rectal carcinoma.Methods: Biopsy samples of tumor and distant normal mucosa from 20 …

    aachen Repository record

  3. Einfluss von Biomaterialien auf die MMP-2-Expression in vivo : Ergebnisse aus dem transgenen Mausmodell

    Kever, Mona2008

    aachen Repository record

  4. Expression, activation, and regulation of matrix metalloproteinase 2 (MMP-2) in the bovine corpus luteum

    Zhang, Bo

    <p>Matrix metalloproteinases (MMPs) have been postulated to be important for angiogenesis and for tissue remodeling events associated with corpus luteum (CL) development. The MMPs are mainly regulated at three levels, transcription, activation, and inhibition by endogenous tissue inhibitors of …

    unh-thes Repository record

  5. Assoziation von MMP-2 Einzelnukleotid-Polymorphismen mit der Prognose von Patienten mit kardiovaskulärer Erkrankung in einem 1-Jahres Follow-Up

    Heller, Florian Dominik2020

    tuebingen

  6. Effect of Methamphetamine on Gingival Fibroblast Production of Matrix Metalloproteinase (MMP)-2 and -9 and Tissue Inhibitor of Metalloproteinase (TIMP)-1 and -2 In Vitro

    Farooqi, Owais Ali2016

    … and periodontitis. Matrix metalloproteinases (MMPs) produced by gingival fibroblasts degrade the extracellular matrix (ECM) and play an important role in periodontitis and oral cancer metastasis. There is no information on effects of METH on fibroblast MMP production, or its role in …

    tenn-hsc Repository record

  7. Effects of systemic flunixin meglumine, topical oxytetracycline, and topical prednisolone acetate on tear film proteinases innormal horses

    Rainbow, Marc E.Virginia Tech2004

    … of two proteinases, matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9), in equine tear film. The study design consisted of twelve ophthalmically normal horses separated into three groups of four in a cross-over study design. Each group was treated for 5 days with flunixin …

    vt Repository record

  8. The Expression of Matrix Metalloproteinase-9 and -2 in Olfactory Injury and Recovery

    Bakos, Stephen2015

    … remain unknown. The matrix metalloproteinases (MMPs) are important components in many central nervous system (CNS) injury paradigms, yet remain unexplored in olfactory injury and recovery. To address the role of MMPs, the temporal expressions of MMP-9 and MMP-2 were examined in 3 olfactory …

    vcu Repository record

  9. Visualizing the Spatial Localization of Active Matrix Metalloproteinases (MMPs) using MALDI Imaging MS

    Muruganantham, Sasirekha2016

    … chemokines, and matrix metalloproteinases (MMPs). The nature of the FBR requires the spatial and temporal regulation of these mediators. MMPs are an extremely large and diverse group of enzymes that play key roles in regulating the FBR. Precise spatiotemporal regulation of MMPs defines their …

    arkansas Repository record

  10. The Examination of Leptin Receptors, Matrix Metalloproteinases-2 and -9 and Tissue Inhibitors of Metalloproteinases in the Rat Cervix

    Rivera, AlexanderUniversity of Illinois at Urbana-Champaign2015

    … has a role in regulating two metalloproteinases (MMP-2 and -9), enzymes known to be involved in collagenolysis. Furthermore, the expression of these metalloproteinase enzymes and their associated inhibitors was examined. Results reported herein show that three of five leptin receptor isoforms are …

    uiuc Repository record

  11. Untersuchungen über die vorteilhaften und nachteiligen Effekte einer späten Reperfusion auf das Remodeling im Restmyokard nach Koronarocclusion bei der Ratte

    Meyer, Bernd JosefUniversität Würzburg

    … für Fibronectin (FN), Matrixmetalloproteinasen (MMPs) und Tissue inhibitors of MMPs (TIMPs) zeigte eine unterschiedliche Expression nach Myokardinfarkt und Reperfusion. Eine Woche nach dem Infarkt kam es zu einer signifikanten Reduktion von TIMP-1, nicht aber von TIMP-2 in allen Infarktgruppen. …

    wurz-thes Repository record

  12. Matrix Metalloproteinases Regulate The Differentiation Of Adipose-Derived Mesenchymal Stem Cells Into Endothelial Cells

    Almalki, Sami G.Creighton University2017

    … prevent restenosis. Matrix metalloproteinases (MMPs) have critical role in the differentiation of MSCs to different lineages. Identifying the molecular factors and mechanisms that regulate AMSCs differentiation to endothelial cells (ECs) is important in the promotion of a greater understanding …

    creighton Repository record

  13. Matrix metalloproteinases in the equine systemic inflammatory response: implications for equine laminitis

    Fugler, Lee AnnBiomedical and Veterinary Medical Sciences - Veterinary Clinical Sciences2022

    … this disease has been associated with increased MMP activity. Therefore, it seems likely that MMPIs could be potential therapeutic agents for laminitis. Further characterization of equine MMPs and evaluation of the effectiveness of MMPIs in the horse are needed. Equine MMP-9 was harvested from …

    lsu-thes Repository record

  14. Valutazione dell'attività delle metalloproteinasi 2 e 9 nelle urine e nel tessuto renale di cani normali e affetti da nefropatia

    Mancini, Danilo <1976>Alma Mater Studiorum - Università di Bologna2008

    Matrix metalloproteinases (MMP) are a large family of proteinases that remodel extracellular matrix (ECM) component. Recent data suggest a role for MMPs in a number of renal pathophysiologies, associated with an imbalance of ECM syntesis and degradation, which may result in an accumulation of ECM …

    bologna Repository record

  15. Der Einfluss von Matrix-Metalloproteinasen und ihrer Inhibitoren auf die Entstehung chronischer Wunden

    Pöpping, KirstenPublikationsserver der RWTH Aachen University2007

    The balance between matrix metalloproteinases (MMP´s) and their inhibitors, the tissue inhibitors of metalloproteinases (TIMP´s), play a central role in the process of physiological wound healing. In the present study levels of MMP-2, -8 and -9, as well as TIMP-1 and -2 were measured in fluids of …

    aachen Repository record

  16. Der Einfluß von Zytokinen und Zell-Zell-Kontakten auf die Expression von Matrix-Metalloproteinasen beim multiplen Myelom

    Kaiser, Martin FlorianPublikationsserver der RWTH Aachen University2005

    … cells. The family of matrix metalloproteinases (MMPs) and its specific inhibitors (TIMPs) represent a group of proteases that can degrade collagenous as well as non-collagenous extracellular matrix. Their expression is elevated in several tumor entities, and their influence on tumor progression …

    aachen Repository record

  17. TIMP-1: Zelluläre Funktion und Beeinflussung der Genexpression von Matrix-Metalloproteinasen in humanen Hepatomzellen

    Lippert, SabinePublikationsserver der RWTH Aachen University2006

    … pathways are involved in the regulation of MMP2 and MMP9 gens as well as how they are influenced by TIMP-1. For this purpose both certain kinases as well as their phosphorylated form (STAT 1, P-STAT 1, STAT 3, P-STAT-3, JAK 1, P-JAK 1, JAK 2, P-JAK 2, Ras GAP and JNK 1) were investigated by …

    aachen Repository record

  18. TIS21 inhibits cell migration and invasion

    임, 서경2011

    … FoxM1 phosphorylation and downregulated MMP-2 expression. In conclusion, TIS21 inhibited cell migration and invasion by inhibition of Src by downregulation of ROS generation in mitochondria, furthermore, TIS21 inhibited FoxM1 phosphorylation and decreased MMP-2 expression. AKT interacted …

    ajou Repository record

  19. Molecular Mechanisms of Interleukin-1beta-Stimulated Regulation of Angiogenesis in Cardiac Microvascular Endothelial Cells.

    Mountain, Deidra Jill Hopkins2007

    … and wound healing. Matrix metalloproteinases (MMPs) are implicated in angiogenesis because of their ability to selectively degrade components of the extracellular matrix. Vascular endothelial growth factors (VEGFs) play a vital role in angiogenesis because of their involvement in the …

    etsu Repository record

  20. The role of matrix metalloproteinases and their inhibitors in irinotecan-induced oral mucositis: an animal model.

    Al-Azri, Abdul Rahman2013

    … enzymes called matrix metalloproteinases (MMPs) have been recently postulated to play a part in mediating the damaging process seen in oral mucositis. It is well established that MMPs and their naturally existing inhibitors (tissue inhibitors of metalloproteinases; TIMPs) maintain a …

    adelaide Repository record

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