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Showing 1 to 13 of 13 for “"MMAD"”.
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Aplicativo de assinatura em documentos digitais nos dispositivos móveis: análise comparativa pelo Método Multicritério de Análise de Decisão (MMAD)
Hundreds of years ago, there was already concern on the confidentiality of information so that the Roman Emperor changed the alphabet of their local language to the Greek letters in an attempt to prevent the enemy understands the message. Apparently, this seems simple, but at the time it wasn't. …
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Development of a Dry Powder Inhaler and Nebulised Nanoparticle-Based Formulations of Curcuminoids for the Potential Treatment of Lung Cancer. Development of Drug Delivery Formulations of Curcuminoids to the Lungs using Air Jet Milling and Sonocrystallisation Techniques for Dry Powder Inhaler Preparations; and Nanoemulsion and Microsuspension for Nebuliser Formulations
… as illustrated FPF 43.4%, 43.6% and 43.4% with MMAD of 3.6µm, 3.5µm and 3.4µm, whereas the best DPI formulation of the air jet milled particles was presented FPF 38.0%, 38.9%, and 39.5% with MMAD of 3.6µm, 3.4µm and 3.2µm for curcumin, demethoxycurcumin and bisdemethoxycurcumin, respectively. …
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PULMONARY DELIVERY OF PNEUMOCCOCAL VACCINE USING NANOCOMPOSITE MICROPARTICLE CARRIERS VIA DRY POWDER INHALATION
… with a porous corrugated surface, 50% yield, MMAD of 1.71±0.10 μm and FPF% of 78.57±0.1%. Adsorption of chitosan hydrochloride (CHL) onto PGA-co-PDL NPs can be used assuccessful strategies to produce cationic NPs. Cationic NPs were prepared with similarparticle size to anionic NPs ≤ …
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Purification and quantitative description of Rhodococcus equi IgG designed for aerosol nebulization to foals
… 2,175 mg/dL and 1,145 mg/dL, respectively. The MMAD of the purified IgG aerosol was 4.7 microns. The mean BAL fluid IgG concentration increased 61% from 19.33 µg/dL at time 0 to 31.5 µg/dL at 0.5 hours, but this increase was not significant (P=0.603). No significant change was observed in …
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Characterization of Perphenazine and Scopolamine Aerosols Generated Using the Capillary Aerosol Generator
… higher powers and low formulation flow rate. The MMAD of scopolamine aerosols was between 0.5 and 2.0µm from 8, 20 and 40mM formulations at 5.0 and 10.0µL/s. The size of scopolamine aerosols increased as a function of increasing the solute concentration. Increasing the formulation flow rate …
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Modified Release of Agglomerated Nano-Particles for Pulmonary Drug Delivery
… have a 1-5 µm Mass Median Aerodynamic Diameter (MMAD). This project prepared agglomerated nanoparticles having modified drug release properties with an aerodynamic particle size suitable for delivery to the lungs.|First, a water-soluble model drug was formulated as microencapsulated dry powders …
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DRY POWDER INHALATION OF PNEUMOCOCCAL VACCINE USING POLYMERIC NANOPARTICLES AS CARRIERS
… and mass median aerodynamic diameter (MMAD) of 1.70±0.03 μm indicating that the majority of the dose would be deposited in the respirable airways of the lungs. The anionic and cationic PGA-co-PDL NPs upon incubation with DCs for 1 h showed an effective uptake as visualised using …
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MicroRNA Nanocarriers for the Treatment of Chronic Obstructive Pulmonary Disease
… showed a mass mean aerodynamic diameters (MMAD) of less than 6 µm indicating the NCMPs would be deposited in the middle to deep lung region and a fine particle fraction (FPF) of 51.33±2.90 %. Internalisation of miR-146a loaded cationic NPs was observed in A549 cell lines using both …
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Creation and validation of an enhanced in vitro model of the lungs
… such as Mass Median Aerodynamic Diameter (MMAD), Geometric Standard Deviation (GSD) and Fine Particle Fraction (FPF) in both the models were compared. The modification using liquid collection surface was chosen for further studies as the parameters obtained in the modified NGI modified did …
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Development of Afatinib lipid nanoparticles targeting non small cell lung cancer
… demonstrated a mass median aerodynamic diameter (MMAD) of 3.24 – 5.85 µm and fine particle fraction (FPF%) of 54.20-33.66%. The particle size of the reconstituted powders was ˂ 100 nm, which is within the size range to be effectively taken up by tumor cells. Assessment of the stability of spray …
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Investigation of Machinability and Dust Emissions in Edge Trimming of Laminated Carbon Fiber Composites
… where mass median aerodynamic diameter (MMAD) was found to be .12 µm - .35 µm when machining at 0o to 135o of fiber direction without using local exhaust ventilation. Real-time particle analysis instruments were introduced into the test protocol which demonstrated the ability to reduce …
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Chemoprevention of Lung Carcinogenesis: Aerosol Administration and Deposition in the Mouse Lung
… solution: with a mass mean aerodynamic diameter, MMAD, at 120 nm) had the highest efficiency. For monodispersed particles, 100 nm particles showed the highest deposition efficiency.</p><p>CONCLUSIONS Aerosol delivery is a promising approach for the chemoprevention of lung cancer. Many natural and …
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Relative bioavailability of terbutaline to the lungs following inhalation using different methods.
… the smallest mass median aerodynamic diameter (MMAD) and the highest fine particle fraction (FPF). The MDI with AMAX resulted in the highest FPD. The in-vitro characteristics of terbutaline sulphate from Bricanyl respules using the Aeroneb Pro (vibrating mesh) and Sidestream jet nebulisers were …