Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"MLN"”.
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Development of an antigen-specific ELISPOT to detect intestinal antibody responses to the swine whipworm, Trichuris suis
… from jejunal region of small intestine (SI-MLN) and cecum in large intestine (C-MLN); and ileocecal Peyer's patches (IC-PP)] and lamina propria from the proximal colon removed from T. suis infected pigs. Tbe local antibody responses were compared to peripheral antibody responses found in the …
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Effects of dietary fermentable material on innate and adaptive immune measures in male and female rats under resting and immunized conditions
… FoxP3+ Treg cells in the mesenteric lymph node (MLN) and spleen than did females. Levels of the regulatory cytokine TGF-β1 also increased in the MLN in a DFM-dependent manner. In contrast, percentages of MLN and splenic CD68+ macrophages and levels of gut tissue IL-10 were higher in females than …
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Engineering resistance to maize lethal necrosis
… emerging maize disease, Maize lethal necrosis (MLN), and engineering resistant maize lines using an artificial microRNA (amiRNA) approach. MLN is a synergistic viral disease caused by the interaction of Maize chlorotic mottle virus (MCMV) with any maize-infecting member of the potyviridae. I …
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An Iolausian endeavour : exploring why the regenerative capacities of insurgent actors weaken
… Movimiento de Liberaci6n Nacional - Tupamaros (MLN-T) of Uruguay, and the Provisional Irish Republican Army (PIRA) of Northern Ireland. At the first level, this thesis examines the extent to which the FLQ, MLN-T, and PIRA's regenerative capacities weakened because of a 'decrease in recruitment' …
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An Iolausian endeavour : exploring why the regenerative capacities of insurgent actors weaken
… Movimiento de Liberaci6n Nacional - Tupamaros (MLN-T) of Uruguay, and the Provisional Irish Republican Army (PIRA) of Northern Ireland. At the first level, this thesis examines the extent to which the FLQ, MLN-T, and PIRA's regenerative capacities weakened because of a 'decrease in recruitment' …
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Methods for Measuring Semantic Similarity of Texts
… decision, we use a Markov Logic Network (MLN). The MLN is based on rich relational features extracted from the output of the predicate-argument alignment structures between T-H pairs. This MLN learns to reward pairs with similar predicates and similar arguments, and penalise pairs …
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Refiguring the sketch : the Nari Gandhi cartographic
… ramifications of the rarity he embodied. A 37 mln film, researched and shot in India, accompanies this text and is the first like and works.
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Immune Checkpoint Blockade Induces Gut Microbiota Translocation That Augments Extraintestinal Anti-Tumor Immunity
… in decreased gut microbiota translocation into MLN and TDLN, diminished DC and effector CD8+ T cell responses, and attenuated response to ICT. Our findings illuminate a key mechanism by which gut microbiota promote extraintestinal anti-cancer immunity.
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Molecular Mechanisms and Antigen Receptor Requirements for Lymphocyte Adaptation to Intestinal Tissues
… from the gut-draining mesenteric lymph nodes (mLN) to the intestinal lamina propria and epithelium (IE). We sought to elucidate the transcriptional mechanisms and T cell receptor (TCR) signaling requirements of CD4+ T cell plasticity and adaptation in the intestinal tissues. Within the …
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Effect of bovine lactoferrin on T lymphocyte cell phenotype and function and the response to vaccination in the neonatal piglet
… cells (PBMC), mesenteric lymph nodes (MLN) and spleen were stained with specific antibodies and identified by using flow cytometry. T-cell and cytokine responses to ex vivo stimulation were assessed by ELISA. Both dietary (SR vs. LF vs. FF) and vaccination effects on immunological …
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The effects of 2’-fucosyllactose and Bifidobacterium longum subspecies infantis supplementation on growth, intestinal development and immune development and function in piglets
… mononuclear cells (PBMC), mesenteric lymph node (MLN) immune cell population and cytokine production in response to ex vivo stimulation in addition to serum cytokines and immunoglobulins. At sacrifice, blood was taken for serum cytokine analysis and immune cells from blood and mesenteric lymph …
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Understanding the Role of Dendritic Cell Subsets in the Generation of a CD8+ T Cell Response Following Pulmonary Vaccinia Viral Infection
… DC and CD11b+ DC) and draining lymph nodes (MLN) (CD8α+), and as such, all are potential regulators of T cell activation (for review see1,2). These studies sought to understand how DC subsets contribute to the generation of virus-specific CD8+ T cells following pulmonary viral infection.
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Phenotype and function of intestinal CD103+ dendritic cells
… mucosa and draining mesenteric lymph nodes (MLN) have an enhanced ability to deliver RA signals and induce gut homing receptors on responding T cells in vitro compared to CD103- DCs and CD103+ DCs outside the intestine. Importantly we show that that CD103+ DCs also are present in human MLN …
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The role of NF-kB2 in secondary and tertiary lymphoid tissue development
… Most strikingly, we show recovery of iLNs and mLN development in one of five \(p100\)\(\Delta\)\(LT\)\(\alpha^{-/-}\) mice generated. These findings demonstrate that the alternative NF-\(\kappa\)B pathway plays an important role in not only SLO development and splenic organisation, but also in …
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Immune activation at the lung epithelial barrier
… in the lung and antigen presentation in the MLN. Adoptive transfer of purified bone marrow monocytes into DC- depleted mice resulted in conversion of injected monocytes into monocyte-derived DCs and presentation of the antigen in the MLN. In chapter 4 we describe that bile acid …
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The role of the inflammatory chemokine receptor CCR2 in immune responses to respiratory viral infection
… CCR2 was highly expressed in CD8⁺ T cells in the mLN, spleen, peripheral blood, and lung parenchyma. Further investigation revealed that CCR2 was expressed within the first T cell division in the mLN, and maintained broad and high expression across all effector and memory T cell subsets. Despite …
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Characterisation of human enteroendocrine cells in organoid models
… guide future investigations. We next generated MLN-Venus and MLN-GCaMP7s duodenal organoids, and used these to carry out the first in-depth transcriptomic and functional characterisation of human motilin-expressing M-cells. Several receptors important for the postprandial and interdigestive …
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Immunomodulatory effects of dietary fibre supplementation: effects on cytokine and antibody production and lymphocyte population profiles
… IgA in the cecal contents was decreased while MLN B cell numbers increased in response to dietary wheat bran fibre. It was observed that neither wheat bran or oat bran treatments exerted any pro-inflammatory effects, with oat bran actually improving antioxidant status. These results suggest …
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Immune response to and pathogenesis of porcine epidemic diarrhea virus
… the small intestine and mesenteric lymph node (MLN) in which viral RNA continued to be detected at 28 dpi. The virus could be isolated from MLN until 14 dpi. The findings from the study did not support the contribution of non-intestinal tissues to fecal shedding for the extended period (35 dpi). …
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Étude de la réponse immune lymphocytaire T CD8[indice supérieur +] suite à une infection par un virus Influenza pandémique
… des DCs tissulaires au ganglion du médiastin (MLN) ce qui peut contribuer à une activation moins efficace des lymphocytes T. Ainsi, la trop forte réponse innée et l’inflammation exagérée compromettent la survie en induisant de graves dommages pulmonaires. De plus, les DCs peuvent suractiver les …
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