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Showing 1 to 1 of 1 for “"MLL4, epigenetics, 3D genome organization, chromatin, Polycomb, Kaubki syndrome"”.
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The role of MLL4 in the chromatin framework: from the epigenome to 3D genome organization
MLL4 is a histone methyltransferase of the Trithorax (TrxG) group, crucial for maintaining active gene expression by antagonizing Polycomb (PcG) proteins, which enforce repressive states. Proper TrxG-PcG crosstalk is critical for various cellular processes and for determining cell fate. Although …