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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 141 for “"MLE"”.
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Investigation of the roX RNAs and the RNA Helicase MLE in Dosage Compensation in Drosophila melanogaster
… proteins, including the RNA helicase Maleless (MLE). MLE contains two highly conserved double stranded RNA binding domains (DRBDs) at the N terminus. We investigated the roles of the roX RNAs and MLE helicase through experiments using classical genetic methods to generate and analyze the effects …
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Divergent Evolution of Enzymatic Activity: Functional Assignment and in Vitro Evolution in the MLE Subgroup of the Enolase Superfamily
… change in the muconate-lactonizing enzyme II (MLE II) from Pseudomonas sp . P54. The single amino acid changes in the AEE and the MLE II mutants are homologous in position, located in the active site at the end of the eighth beta-strand of the (beta/alpha)8-barrel. Substrate design was used to …
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Analysis of the use of mother tongue based-multilingual education (MTB-MLE) strategies by teachers in lower primary grades in Chongwe rural district.
… (i) to establish teachers’ understanding of MTB-MLE strategies used in the classroom. (ii) to analyse teachers’ use of MTB-MLE strategies in lower grades of Primary school. (iii) to identify the challenges that teachers face when applying MTB-MLE strategies in lower grades of primary school. The …
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Analysis of the use of mother tongue based-multilingual education (MTB-MLE) strategies by teachers in lower primary grades in Chongwe rural district.
… (i) to establish teachers’ understanding of MTB-MLE strategies used in the classroom. (ii) to analyse teachers’ use of MTB-MLE strategies in lower grades of Primary school. (iii) to identify the challenges that teachers face when applying MTB-MLE strategies in lower grades of primary school. The …
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Study of Enzyme Evolution Within the MLE Subgroup Focusing on Characterizing Member Enzymes for the Purpose of Discovering Relationships Among Sequence, Structure, and Function
… in Nature while the muconate lactonizing enzyme (MLE) subgroup represents the most divergent in chemical reactions in the superfamily; therefore, the MLE subgroup is an excellent candidate to appreciate chemistry driven evolution of enzymes. The MLE subgroup, whose members have diverse sequences …
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The Economic and Technical Feasibility of the Application of Partial Nitritation Anammox Technology Over Conventional Nitrification Denitrification for the Treatment of Sidestream Liquor at Cape Flats WWTP
… denitrification (Modified Ludzack-Ettinger (MLE) configuration) with a novel partial nitritation/ anammox (PN/A) process. The sidestream liquor was characterised by mass balance over the AD process. Steady-state models were used to predict equipment sizes and determine the process efficiency …
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China's New Maritime Legal Enforcement Strategy in the South China Sea: Legal Warfare and an Emerging Contest Over Norms at Sea
… to implement a new Maritime Law Enforcement (MLE) strategy in the South China Sea. This new MLE strategy utilizes vessels from China's rapidly expanding MLE agencies, reinforced by PLA naval and other military assets, to assert the country's claims against other Southeast Asian claimants, …
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Maximum likelihood parameter estimation in time series models using sequential Monte Carlo
… algorithms for maximum likelihood estimation (MLE). In the last two decades, the range of statistical models where parameter estimation can be performed has been significantly extended with the development of Monte Carlo methods. We provide contribution to the field in a similar manner, namely …
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Robust mixtures of regression models
… param- eters by the maximum likelihood estimate (MLE). In this project, we demonstrate that the MLE, like the least squares estimate, is sensitive to outliers and heavy-tailed error distributions. We propose a robust estimation procedure and an EM-type algorithm to estimate the mixture regression …
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A Bayesian solution to non-convergence of crossed random effects models
… stimuli; however, maximum likelihood estimation (MLE) and restricted maximum likelihood (REML) estimation often encounter convergence problems, which in turn lead to researchers fitting simpler models (e.g., only random intercepts). If the random effect structure is too simple, tests of fixed …
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Chaotic Dynamics of Polyatomic Systems with an Emphasis on DNA Models
… by computing the maximum Lyapunov exponent (mLE) across a spectrum of temperatures, and the effect of base pair disorder on the dynamics is investigated. In addition to the inherent heterogeneity due to the proportion of adenine-thymine (AT) and guanine-cytosine (GC) base pairs, the …
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Assessment and Comparison of Techniques for Transforming Parameters to a Common Metric in Item Response Theory
… of squares criteria. The remaining technique (MLE) finds the scale transformation that maximizes the likelihood of observing vectors of item parameter differences. Results indicate that for calibrations with a small number of items with extreme estimated difficulty values all techniques perform …
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Evaluation of landfill leachate treatability in a modified Ludzack Ettinger activated sludge system
… system utilizing the Modified Ludzack Ettinger (MLE) nitrification/denitrification process with the addition of phosphorus and methanol was operated to determine its effectiveness in removing total nitrogen, organic compounds and metals from the leachate. The system was compared with the …
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Some applications of minimum norm quadratic estimation and eigenvalue-based test for heteroskedasticity
… MINQUE and the maximum likelihood estimator (MLE) for a p th-order ARCH. The relation suggests that MINQUE is a more general procedure than the MLE. Also, the use of MINQUE may be thought of as a way to provide some kind of ""adjustment"" to the small sample bias of the MLE. Based on the …
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Essays On Spatial Econometrics: Estimation Methods And Applications
… prove that the maximum likelihood estimator (MLE) is generally inconsistent when heteroskedasticity is not taken into account in the estimation. We show that the necessary condition for consistency of the MLE depends on the specification of the spatial weight matrices. Then, we extend the …
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Estimation in random field models for noisy spatial data
… properties of the Maximum Likelihood Estimator (MLE) of an Onrstein-Uhlenbeck process model with measurement error are studied. The effect caused by adding measurement error, or ""nugget,"" is revealed by the fixed region asymptotics of the MLE. The kriging predictor with estimated covariance is …
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Inverse uncertainty quantification of input model parameters for thermal-hydraulics simulations using expectation-maximization under non-Bayesian and Bayesian framework
… using the Maximum Likelihood Estimate (MLE) and Maximum a Posteriori (MAP) estimate. The difference between experimental measurements and nominal code predictions, which are the observables, are considered scalar random variables. A dispersed normal prior is assumed on the mean and an …
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Comparison of Aeration Strategies for Optimization of Nitrogen Removal in an Adsorption/Bio-oxidation (A/B) Process with an Emphasis on Ammonia vs. NOx (AvN) control
… fully-intermittent and 2) intermittently-aerated MLE configurations was compared to DO Control and ABAC, each with continuous aeration, in an MLE configuration. The study also examined operation of each aeration strategy with two different feed types: A-Stage effluent (ASE) and primary clarifier …
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Mechanistic Investigations of Mandelate Racemase: The Electrophilic Catalysts
… for MR, muconate lactonizing enzyme (MLE), galactonate dehydratase (GalD) and glucarate dehydratase (GlucD) were determined. MR and MLE bind and require a single metal ion for activity. GalD and GlucD require two metals for activity and show inhibition at high metal ion concentrations …
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Shape-Constrained Inference for Concave-Transformed Densities and their Modes
… the log-concave maximum likelihood estimate (MLE) to the MLE over the constrained subclass of log-concave densities with a fixed mode. The test can be inverted to form a confidence set. We study the properties of the constrained MLE and the Wilks phenomenon of the likelihood ratio statistic. …
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