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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"MKS"”.
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The role of megakaryocytes and platelets in infection and immunothrombosis
Megakaryocytes (MKs), one of the largest and rarest hematopoietic stem cells in the bone marrow, have traditionally played a primary role in hemostasis as precursors to platelets, which are importantly, one of the most abundant cell types in the peripheral circulation. While platelets are studied …
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Platelet Dense Granules Mature Within Late Stages Of Megakaryocyte Differentiation By Cargo Delivery
… (MK). DGs are thought to fully mature within MKs prior to platelet formation. Here I challenge this notion by exploiting vital fluorescent dyes to distinguish mildly acidic DGs from highly acidic compartments in platelets and MKs. In mouse platelets, compartments labeled by mepacrine — a …
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Model Order Reduction in Structural Mechanics
… in Hinsicht auf den später beschriebenen FEM-MKS-Kopplungsprozess. Die Effizienz der MOR-Methoden wird sowohl hinsichtlich der Qualität der ROM als auch bezogen auf die hierfür benötigte Rechenzeit bemessen. Aus diesem Grunde wurden etliche MOR Schemata dargelegt, mit dem Ziel, den …
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The psychological well-being of missionary kids
… the psychological wellbeing of missionary kids (MKs) after they return from the mission field to the culture designated by their passport. Past literature addressing MK well-being was reviewed and it was determined attachment with parents, experiences of trauma, cultural adaptation, and social …
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Vergleich der biochemischen Qualität von Erythrozytenkonzentraten, gewonnen durch Multikomponentenspende oder herkömmliche Vollblutspende und Einfluß auf ausgewählte biochemische Laborparameter und in-vivo-Mikrozirkulation des Spenders
… (VBS) bzw. maschineller Multikomponentenspende (MKS) gewonnen und über einen Zeitraum von 63 Tagen gelagert wurden. Dabei wurde die Überlebensfähigkeit der roten Zellen anhand des ATP-Gehaltes, ihre Sauerstoffabgabefähigkeit mittels des 2,3-DPG-Spiegels sowie die Zellschädigung durch die …
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Vergleich der rheologischen Qualität von Erythrozytenkonzentraten, gewonnen durch herkömmliche Vollblutspende oder Multikomponentenspende und Einfluß der Entnahmeverfahren auf ausgewählte rheologische Laborparameter und in-vivo-Mikrozirkulation des Spenders
… und einer maschinellen Multikomponentenspende (MKS) teil. Die erzeugten leukozyten-depletierten Erythrozytenkonzentrate beider Gruppen wurden mittels CPD-50 antikoaguliert und über einen Zeitraum von 63 Tagen in PAGGS-Mannitol gelagert. Beurteilt wurden zum einen rheologische in-vitro-Parameter …
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The role of Nbeal2 in the homeostasis and retention of granules in haematopoietic cells
… of actin-related processes in megakaryocytes (MKs) and platelets, which showed that MKs from Nbeal2−/− mice exhibit appropriate proplatelet formation, but thrombin- activated Nbeal2−/− platelets do not appropriately express F-actin. The reduced abundance and mislocalisation of Dock7, and the …
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Genetic and functional studies in inherited platelet disorders
… engulfment of neutrophils by megakaryocytes (MKs)) is observed, as well as an increased incidence of early onset fibrosis. Nbeal2−/− mice have defects of secretory granules in a variety of myeloid and lymphoid cells, increased susceptibility to infection, and their MKs have a proinflammatory …
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Calibration and performance of a selective catalytic reduction (SCR) bench rig for NOx̳ emissions control
… of test gases, and a connection with an MKS NOx Analyzer, the rig allows for a vast range of SCR test conditions, and can easily be adapted for degreening, aging, and the implementation of other technologies onto the rig. To calibrate the test rig, baseline parameterization of a Cu-based …
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Raman spektroskopische Untersuchung von einphasigen strukturierten Stoffgemischen in einem Mikrokapillarsystem
… Stoffgemische in einem Mikrokapillarsystem (MKS) mittels optischer Messtechnik hinsichtlich ihrer molekularen Strukturierung untersucht. Dies wurde durch die Kombination unterschiedlicher Auswertemethoden ermöglicht, welche alle gemeinsam haben, dass sie auf der Auswertung des Schwerpunktes …
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N2, O2, and NF3 Dissociation in a Low Frequency, High Density Plasma Source
… toroidal remote plasma source from MKS Instruments, operating at a power density of 5 – 50 W/cm3. The dissociation of O2 drops from 60% to 10% with an increase of O2 percentage. For NF3, the dissociation to form F rises with an increase of NF3 percentage from 20% at 1% NF3 to 100% at …
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Regulation of GAP1 permease sorting in Saccharomyces cerevisiae
… plasma membrane. In contrast, deletion of the MKS] gene, which encodes a negative regulator of glutamate synthesis, increased glutamate and glutamine levels and increased sorting of Gaplp to the vacuole. We also found that the LST8 gene, which was previously implicated in the regulation of Gap …
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Cytokine receptor-like factor 3 (CRLF3): A novel regulator of platelet biogenesis and potential drug target for thrombocythaemia
… as yet we have not been able to generate enough MKs to have adequate material to perform immunoprecipitation assays. Therefore, the interactome of CRLF3 in MKs remains unknown. In conclusion, we identified a mechanism by which Crlf3 controls platelet biogenesis. Slowed maturation of Crlf3-/- …
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Analysis of gas phase composition in fuel and exhaust gas in Solid Oxide Fuel Cells
… path of the gas flow. The mass spectrometer, a MKS Cirrus system, has a mass range of 1--100 amu and a detection limit of ∼0.001 torr. The mass spectrometry is applied to full-cell tests. The cell is operated in H 2 as fuel. The cell is tested with and without 10--20 torr water added, with …
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Molecular regulation of BRD3 in forward programming of Megakaryocytes
… These cells were capable to differentiate into MKs, using a forward programming protocol, demonstrating that BRD3 is not essential for MK differentiation. I found that a subset of genes was differentially expressed in the absence of BRD3, despite genome-wide chromatin accessibility and H3K27ac …
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Study of surface kinetics in PECVD chamber cleaning using remote plasma source
… one approach to the characterization of plasma. MKS Astex plasma source has a very high power density. Compared to a typical industrial plasma source, the power density of the TCTP source is two orders of magnitude higher. The extremely high power density makes the plasma source very unique and …
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Beyond the rare blood group Vel, uncovering the functions of SMIM1 in blood and in other organs
… that SMIM1 is expressed in megakaryocytes (MKs), platelets, neutrophils and naïve, memory and class-switched B-lymphocytes. I further demonstrated that SMIM1 localisation and the type of multimers it forms in some of those cells are cell type dependent. Second, I assessed the effect of the …
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Internationalisation of the National Aspirations of the Palestinian Arab Citizens of Israel
… serve as a strategic information source for Arab MKs, NGOs and Israeli decision makers.
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Fermentation of vitamin K2 (menaquinone-7): Development of an optimal fermentation process to selectively enhance the production of the biologically significant all-trans isomer
… far more diverse. In particular, menaquinones (MKs) offer more significant health gains than phylloquinone (PK) and have been associated with the prevention of osteoporosis and cardiovascular diseases (CVDs) and decreasing the risk of and improving the outcomes associated with several illnesses …