Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"MK801"”.
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Angiotensin II Modulation of NMDA Receptor Function: Characterization of Mechanisms Attenuating Excitotoxicity in Neurons
… with NMDA, and this reduction was inhibited by MK801. Addition of Ang II suppressed the NMDA receptor-mediated reduction in Bcl-2. The Ang II effect on NMDA-mediated changes in Bcl-2 expression was blocked by PD 123319, but was not significantly altered by losartan. Taken together, these results …
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Excretory nitrogen metabolism in the Chinese soft-shelled turtle, pelodiscus sinensis
… a sub-lethal dose of NH4Cl. Through the use of MK801 (an NMDA receptor antagonist) and MSO (a glutamine synthetase inhibitor) prior to a lethal dose of NH4Cl, it appears that ammonia toxicity in P. sinensis involves the activation of NMDA receptors and that glutamine accumulation could not be …
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A toxicological analysis of the cyanotoxin β-methylamino-L-alanine at multiple neural levels and identification of novel modes of activity
… N methyl-D-aspartate (NMDA) receptor antagonist MK801 indicates that the neurotoxic effects of BMAA are mediated via NMDA receptor activation. Immunocytochemical stains show that BMAA induces the expression of neuronal nitric oxide synthase (nNOS) and caspase-3 indicating that it can stimulate …
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Roles of interleukin-1 beta in glutamate-induced spinal cord injury
… AMPA and NMDA receptors on IL-1â and IL-1ra, MK801 and NBQX were applied individually on the spinal cord with glutamate. The results show that both AMPA and NMDA receptors are involved in glutamate-induced reciprocity between IL-1â and IL-1ra. To determine if this reciprocity between the …
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Mechanismen, die nach NMDA-Rezeptor-Blockade zur disseminierten Apoptose im sich entwickelnden Rattengehirn führen
Das sich entwickelnde Rattengehirn ist sehr anfällig gegenüber einer Blockade des N-methyl-D-aspartat-Rezeptors (NMDA). Dies kann zu einer schweren, disseminierten apoptotischen Neurodegeneration führen. In dieser Arbeit werden vor allem 2 Effekte aufgezeigt, die nach systemischer Verabreichung des …