Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"MK-571"”.
-
Promoter Polymorphisms of Cysteinyl Leukotriene Receptor 1 (CysLTR1) Influence the Effect of Leukotriene Modifier on Transcriptional Regulation of the CysLTR1 Gene Induced by IL-4
… CysLTR1-mediated mechanism. Leukotriene modifier MK-571, a selective CysLTR1 antagonist, is widely used in the management of asthma. We selected Cysteinyl leukotruene receptor 1 (CysLTR1) among leukotriene ？ related genes and screened for genetic variation in the 5？ upstream region of CysLTR1 …
-
Effect of Cysteinyl Leukotriene D4 on Chemokine Expression via Cysteinyl Leukotriene Receptor 1 in Human Lung Epithelial Cells, A549
… cells were pre-treated with CysLTR1 antagonist, MK-571 100nM for 3hrs. To confirm the effect of LTD4 and/or CysLTR1 on releasing MCP-1 and IP-10, ELISA was performed with cell supernatant. RESULT: mRNA expression level of MCP-1 was augmented as soon as treated with LTD4. mRNA expression level of …
-
Design, Synthesis and Biological Screening of Novel Cucsinspired Estrone Analogues Towards Treatment of Hepatocellular Carcinoma
… 46%, 30% and 22%; respectively, in comparison to MK-571, which known MRP1 inhibitor. Our study demonstrated the design, synthesis of novel CIEA analogs of potent antiproliferation/ anticancer activities toward hepatocellular carcinoma and potential application to overcome cancer resistance to …