Global ETD Search
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Showing 1 to 12 of 12 for “"MITOGEN STIMULATION"”.
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Compartmental Hepatitis B Virus (HBV) Evolution, Replication and Infectivity in vivo and ex vivo
… with development of fulminant hepatitis B. Mitogen stimulation in PBMC of CHB patients revealed presence of replicating HBV, which can be upregulated in PBMC and exhibited infectious capacity to HepaRG cells in vitro. In summary, our data suggests potent NAs have little effect on HBV cccDNA …
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The Immune Status of Two Bloom's Syndrome Siblings
… chemotaxis, nitroblue tetrazolium (NBT), mitogen stimulation and mixed lymphocyte culture (MLC). Findings. Results are compared with those of other known BS subjects. Analysis of our patients' immune systems seems to agree with findings of previous studies. Conclusion. While there is a …
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Cell-Mediated Cytotoxicity of Jensen Tumor in Sprague-Dawley Rats
… well with the in vivo tumor status. Lymphocyte stimulation with Phytohemmag-glutinin (PHA, a T cell mitogen) was decreased in persister rats; while Poke Weed mitogen (PWM; a B cell mitogen) stimulation was increased in persister rats. Treatment of "immune" lymphocytes with a) supernatants from …
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Acute Effects of Whole-Body Proton Irradiation on the Immune System of the C57BL/6 Mouse
… Splenic T cells showed reduced responsiveness to mitogen stimulation for the first four days post- WBI, while splenic B cell responsiveness was reduced at all time periods. Analysis of hematological parameters showed depression of red blood cells, hemoglobin concentration, and hematocrit levels …
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Molecular Mechanisms Underlying Innate Immune Kinase TBK1-Driven Oncogenic Transformation
… bound to components of the exocyst complex. Upon mitogen stimulation, triggering of the innate immune response, re-exposure to glucose, or oncogene activation, TBK1 is recruited to the exocyst, where it activates AKT. In cells lacking TBK1, insulin activates AKT normally, but AKT activation by …
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Metabolic Modulation Of Mammalian Dna Excision Repair
… and lectin-stimulated bovine lymphocytes. Upon mitogenic stimulation, UVL-induced repair increased by a factor of 2 to 3, and reached this maximum 2 days before the onset of DNA replication. However, DMS-induced repair increased sevenfold in parallel with DNA replication. Repair patch sizes were …
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Molecular Characterization of Fowlpox Virus Isolates and Evaluation of Recombinant Vaccines Generated for Protection Against Fowlpox and Reticuloendotheliosis
… associated suppression of lymphocyte response to mitogen stimulation due to REV infection was not detected, suggesting that other immuno-suppressive mechanisms are involved. Since, under natural conditions, chickens become dually infected with both FPV and REV, a FPV recombinant expressing the REV …
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Analysis of the Metabolism of Dextran-Methylprednisolone Succinate Using
… regarding rat spleen lymphocyte isolation and mitogen stimulation were performed. Optimum conditions for culture of spleen lymphocytes require RPMI-1640 to be supplemented with 2.5% rat serum. Separation of rat liver cells was accomplished by perfbsion of the liver with HEPES buffer containing …
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The effect of dietary vitamin E on the humoral and cell-mediated immune response of pigs housed at different environmental temperatures or weaned at various ages
… at 19°C compared with pigs housed at 30°C, but mitogen stimulation indices of white blood cells, plasma cortisol levels, and antibody titers were similar. Serum and liver vitamin E levels linearly increased with increasing dietary vitamin E level, but performance, cortisol, antibody levels and …
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IL-2 and Antisense TGF-B1 Gene Therapy of the H238 Tumor and Analysis of TGF-B Receptors
… cells showed almost no tumor incidence (0-20%). Mitogen stimulation of splenocytes from tumor bearing and non tumor bearing animals showed significant differences. Splenocytes from non tumor bearing animals displayed a higher stimulation index than from tumor bearing animals, probably alluding to …
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Immune parameters as predictors of response to maintenance therapy in low grade non-Hodgkin's lymphoma patients
… killer activity (NKA), α-IFN enhanced NKA, mitogen and antigen proliferation, lymphokine activated kill against both KS62 and Daudi targets, phenotypic analysis of circulating lymphocytes, assessment of IL-2 levels after mitogen stimulation of lymphocytes, as well as the determination of …
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ΕΠΙΔΡΑΣΗ ΤΟΥ ΦΟΡΒΟΛΙΚΟΥ ΕΣΤΕΡΑ ΤΡΑ ΣΕ ΑΝΘΡΩΠΙΝΑ ΛΕΥΧΑΙΜΙΚΑ ΛΕΜΦΟΚΥΤΤΑΡΑ
IN THIS STUDY WE HAVE INVESTIGATED THE EFFECT OF THE PHORBOL ESTER 12-O-TETRADECANOYLPHORBOL-13-ACETATE (TPA) ON TWO HUMAN LEUKEMIC CELL LINES: 1) THE MOLT3 CELL LINE, WHICH SHOWS TWO PHENOTYPES, THAT OF LARGE THYMIC BLASTS (ABOUT 50% OFTHE CELLS). 2) THE SDK CELL LINE, WHICH INCLUDES CELLS WITH …