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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 593 for “"MIR"”.

  1. Distinct roles of miR-146a and miR-146b in neurons and microglia

    Chithanathan, Keerthana2025

    tartu

  2. Mir-484 Functions As An Onco-Mir In Triple Negative Breast Cancer

    Kabil, Nashwa, <p>0000-0002-5413-849X</p>2019

    … Numerous studies have indicated that microRNAs (miRs) have an important role in BC progression, invasion, angiogenesis, and metastasis. We analyzed miRNA expression profiles of BC patient data bases and identified that miR-484 is highly upregulated in all subtypes of BC patients, with the highest …

    uthsc Repository record

  3. Antagonistic Roles of miR-199a-3p/miR-214 and the miR-200 Family in the Regulation of Uterine Contractility During Pregnancy and Labor

    Williams, Koriand'r2014

    … understood. Recently, we discovered that miR-200 family members, miR-200b and miR-429, and their target, transcription factor ZEB1, serve as P4/progesterone receptor (PR)-mediated regulators of uterine quiescence during pregnancy (Renthal et al., 2010). In the present study, we identified …

    utswmed Repository record

  4. Role of miR-19a-3p and miR-19b-3p in microglia activation and neuroinflammation

    Sahebdel, Faezeh2024

    … pain experienced by many with SCI. MicroRNAs (miRNAs) have emerged as significant regulators of neuroinflammation. Previous research from our lab identified elevated levels of circulating miR-19a and miR-19b in individuals with SCI who suffer from neuropathic pain compared to those without …

    umn Repository record

  5. Evaluation of miR-497 & miR-219 as non-invasive biomarkers for meningioma and glioma

    Abdelrahman, Ahmed2023

    … diagnosis and classification. Circulating miRNAs have shown potential as cancer biomarkers in various tumours. This study evaluated specific miRNAs, miR-497 and miR-219, as convenient and efficient predictors of meningioma and glioma grades. MiR-497 was selected based on preliminary results …

    plymouth Repository record

  6. MIR-Evaneszentwellenspektroskopie mit niedermodigen Wellenleitern

    Hahn, Peter

    … im Wellenlängenbereich des mittleren Infrarot (MIR, 2,5-25µm) eingesetzt. Zur Steigerung der Empfindlichkeit kam eine Festphasenextraktionsmethode zur Anwendung, durch die der Zielanalyt vom stark absorbierenden Wasser getrennt wird. Dies geschieht durch Anreicherung des Analyten in einer …

    freiburg-diss Repository record

  7. Differences in miR-122 and miR-191 Expression in HBV- versus HCV-associated Hepatocellular Carcinoma

    Spaniel, CarolynThe University of Texas Medical Branch at Galveston2016

    … studies have suggested that the expression of miR-122 and miR-191 is decreased and increased, respectively, in hepatocellular carcinoma. However, other evidence suggests miR-122 may be preserved in HCV-associated hepatocellular carcinoma (HCC). The goal of this thesis is to assess miR-122 and …

    utmb Repository record

  8. The Roles of miR-155 and miR-15/16 in Natural Killer Cell Function and Maturation

    Sullivan, Ryan Patrick2015

    … risk of developing cancer.</p><p>Micro-RNAs (miRNAs) regulate numerous cellular functions. MiRNA genes are transcribed as long primary (pri-miRNA) transcripts that are subsequently 'cropped' by the Drosha/Dgcr8 complex into precursor miRNAs (pre-miRNA) that have a characteristic stem-loop …

    wustl Repository record

  9. MicroRNAs in early embryonic development : dissecting the role of miR-290 through miR-295 in the mouse

    Dennis, Lucas MMassachusetts Institute of Technology2008

    … of target mRNAs. Targeted deletion of the miRNA biogenesis machinery in the mouse has demonstrated essential roles for miRNAs during early development. In this thesis, I have examined the role of a family of miRNAs, miR-290 through miR-295 (miR-290 cluster), which are specifically expressed …

    mit Repository record

  10. Evaluation of nanoscale delivery of miR 216 a/b, miR 217, and gemcitabine in pancreatic cancer cell lines

    Tran Hoang, ChristineUniversity of Missouri--Columbia2025

    … cancer diagnostics and therapeutics. MicroRNAs (miRNAs), a class of non-coding RNAs that regulate gene expression, have emerged as potential tools for early detection, prognosis, and therapeutic intervention in PDAC. Tumor-suppressive miRNAs such as miR-216a and miR-217 are typically …

    missouri Repository record

  11. miR-148b as a candidate for targeted cancer therapy

    Taverna, Daniela, Quirico, LorenaUniversità degli Studi di Torino2018

    unito Repository record

  12. miR-137, schizophrenia and sleep regulation in Drosophila melanogaster.

    Grimes, Kalon P.Bournemouth University2020

    … of target mRNAs. The evolutionarily conserved miR-137 is expressed in invertebrate and mammalian neuronal tissue and there is experimental evidence for mir-137 regulating neurological development, synaptic plasticity, and cognitive function. Other genes likely regulated by miR-137 include …

    bournemouth Repository record

  13. Role of miR-483 in pancreatic alpha and beta cells

    Mohan, Ramkumar

    mtu Repository record

  14. A Neuroprotective Role for Mir-1017, a Non-Canonical Mirna

    de Cruz, Matthew2019

    <p>miRNAs are post-transcriptional regulators of gene expression, with numerous being involved in neurobiology. Within the human genome a quarter of the identified miRNA loci derive from a class of miRNAs termed tailed mirtrons. Despite the identification of this large population of miRNA, no …

    usm Repository record

  15. Study of the role of miR-204 in photoreceptor development

    Bhat, Rajeshwari SubrayThe Open University2016

    MicroRNAs (miRNAs), a class of small non-coding RNAs with a basic role in post-transcriptional regulation of gene expression, are emerging as key players in the control of fundamental biological processes during the differentiation of many tissues and organs. The goal of my thesis is to shed light …

    the-open-u Repository record

  16. Investigating the role of miR-21 in autophagy and VMP1

    O'Leary, Kate MarieThe University of Edinburgh2017

    … methylated region (DMR) around the miR-21/VMP1 locus in IBD patients compared to HC and elevated levels of VMP1 and miR-21 have been detected in patients. MiR-21 is a microRNA that is associated with immune related disorders, and VMP1 Is a key regulator of autophagy, a pathway …

    edinburgh Repository record

  17. Generation, manipulation and detection of NIR and MIR entangled photon pairs

    Trenti, AlessandroUniversità degli studi di Trento2018

    … waveguides, with the final goal to generate MIR entangled photon pairs via SPDC. Alongside, the generation and manipulation of correlated photon pair sources by means of spontaneous FWM in traditional silicon waveguides and microring resonators at telecom wavelength was also investigated. For …

    trento Repository record

  18. Deciphering The Role of miR-506 in Ovarian Cancer Drug Sensitivity

    Nicoletti, RobertaThe Open University2018

    … disease. Due to their master regulatory role, miRNAs are considered powerful tools to obtain representative molecular portraits of specific tumour characteristics and behaviours. My laboratory performed microRNA expression profiles on advanced stage EOC patients and a cluster of miRNAs, …

    the-open-u Repository record

  19. Exploring miR-142-3p in cervical cancer: Implications for treatment response

    Van der Merwe, Michelle PaulineStellenbosch : Stellenbosch University2026

    … limits therapeutic success. MicroRNAs (miRNAs) and extracellular vesicles (EVs) have emerged as important regulators of tumor behavior, with the potential to influence both treatment response and tumor-microenvironment interactions. miR-142-3p is widely recognized as a tumor-suppressive …

    stellenbosch Repository record

  20. Identifying The Roles of miR-17 in Ciliogenesis and Cell Cycle

    Alanazi, Ashwaq2024

    … proliferation mechanisms. MicroRNAs, especially miR-17, contribute to cell cycle regulation and proliferation. Recent investigations have highlighted the dysregulated expression of miR-17 in various malignancies, underlining its potential role in cancer. However, the correlation between primary …

    chapman Repository record

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