Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"MHC polymorphism"”.
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MHC Class I diversity influences haematozoon infection intensity in the polymorphic black sparrowhawk (Accipiter melanoleucus)
The major histocompatibility complex (MHC) is a multigene family known to be the most variable gene group in vertebrates in terms of allelic diversity and gene number. Pathogen mediated selection is thought to be the major driving force behind the unusually high levels of MHC polymorphism in …
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Host-parasite co-evolution and genetic variation at the major histocompatibility complex in the Trinidadian guppy (poecilia reticulata)
The Major Histocompatibility Complex (MHC) is a region of the vertebrate genome believed to be responsible for an individual's ability to detect and recognise invading parasites. The MHC molecule has been shown to bind to short fragments of parasite and present these to the adaptive immune system. …
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Immunogenetics of free-ranging felids on Namibian farmlands
… diseases. The Major Histocompatibility Complex (MHC) is a gene family that plays a central role in the vertebrate’s immune system by triggering the adaptive immune response after exposure to pathogens. MHC genes have become highly suitable molecular markers of adaptive significance. They …
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Novel peptide antigens provide insights into the recognition process by T cells
… (Trp and Arg) at position 97 in mouse and human MHC proteins. These polymorphisms in the human gene HLA-B have recently been associated with HIV control (tryptophan), or progression (arginine) to AIDS. My findings showed that the same polymorphism in position 97 in the mouse protein Ld resulted …
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Evolution of major histocompatibility complex genes in New World bats and their functional importance in parasite resistance and life-history decisions in the lesser bulldog bat (Noctilio albiventris)
… genes of the major histocompatibility complex (MHC) constitute a central component of the adaptive immune system and play an essential role in parasite resistance and associated life-history strategies. In addition to pathogen-mediated selection also sexual selection mechanisms have been …