Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"MF59"”.
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Impact of Adjuvants on the Antibody Responses to Pre-pandemic H5N1 Influenza Vaccines
… especially the oil‑in‑water emulsions (such as MF59) in combination with H5N1 split or subunit vaccines. While the ability of these adjuvants to generally boost the vaccine-specific antibody titers has been well documented, the question of how adjuvants modulate the quality of such responses …
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The rational structure-based design of a protein nanoparticle presenting a chimeric MenB antigen
… of immunogenicity as a commercially available MF59-based emulsion adjuvant. Further serological assays were performed to gauge the bactericidal titre resulting from immunisation with the nanoparticle. The work within this project exemplifies a structural vaccinology approach towards the design …
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Adjuvant Interactions with Lipid Membranes and Their Effect on Cellular Immune Responses
… antigen-specific immunotherapy (ASIT). An MF59-analog (MF59a) made in our lab was selected to co-deliver ovalbumin and dexamethasone based on its ability to solubilize dexamethasone, extend its release, and enhance its membrane permeability and internalization. The combination of MF59a, …
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Generation and characterization of HIV-1 subtype C candidate vaccines that will induce high titre antibody responses to HIV-1 envelope glycoprotein
… adjuvants AlhydroGel (similar to alum) or the MF59-like squalene-based oil-in-water nano-emulsion AddaVax. Soluble Env (GNL) adjuvanted in AlhydroGel resulted in improved immune response in rabbits, with significantly higher serum binding antibodies to soluble Env (GNL) and scaffolded CAP256 …