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Showing 1 to 5 of 5 for “"MEXA"”.
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Computational Study on MFP MexA in MexAB-OprM and RND transporter AcrB in AcrAB-TolC Efflux Pumps
… in P.aeruginosa and E.coli / Salmonella, MexAB-OprM and AcrAB-TolC respectively. In particular, we studied the possible multimerization of the MFP component MexA and the effects of mutations in the AcrB distal binding pocket. The starting point for the first part of our study was the …
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Structural and Functional Study of Multidrug Membrane Transporters
… Resistance-Nodulation-Cell Division transporter (MexA,B-OprM) in gram-positive and gram-negative bacteria (<em> Bacillus subtilis</em> and <em>Pseudomonas aeruginosa</em>), respectively. We fused EGFP with N-terminus and C-terminus of BmrA to construct BmrA-EGFP fusion proteins and characterized …
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The potential use of bio-ultracarbofluids in a standard diesel engine
… dynamometer to measure brake power output, and Mexa-321E and Mexa-211E analysers to measure exhaust pollutants. Measurements were made of engine brake power output, carbon dioxide, carbon monoxide, hydrocarbons and smoke emissions over the speed range 1000 to 3000 rpm at 200 rpm intervals. The …
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Model-based experimental analysis of enzyme kinetics in aqueous-organic biphasic systems
… using the model-based experimental analysis (MEXA) approach including a priori simulations, sensitivity analysis, and optimal experimental design. This supports not only the development of mechanistic kinetic models, but also the determination of optimal measurement methods and the development …
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Molecular Mechanisms of Antibacterial Resistance Among Pseudomonas aeruginosa: Multi-Drug Efflux Pumps and Their Interactions with Other Resistance Mechanisms
… four of the well characterized efflux pumps, mexAB-oprM, mexCD-opri, mexEF-oprN, and mexXY, were shown to be expressed in a wild-type susceptible strain of P. aeruginosa. The effect of growth-phase on expression of these pumps had varying results depending upon which RNA isolation method and …