Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"MER11"”.
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Primate-specific KRAB zinc finger proteins and their targets rewire regulatory networks related to inflammation and pancreas development
… and binds on members of primate conserved MER11 elements leading to their epigenetic silencing. On the other hand, ZNF267 is already highly expressed in monocytes and macrophages but it is further upregulated by inflammatory stimuli. ZNF267 ChIP data show that it mainly targets and silences …
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A TRIM28 centric strategy to efficiently uncover the contribution of KZFPs to the evolution of gene regulatory networks
… of pancreas development via the regulation of MER11 elements which, when derepressed, are able to trigger a liver cell fate program. Here I present a new large-scale strategy to uncover links between KZFPs, TEs and gene regulation. We leverage the shared ability of most KZFPs to recruit TRIM28, …