Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"MED23"”.
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Innate sensing and regulation during enteric caliciviruses infections
… interferon sub- types, we show that depletion of MED23 leads to a reduction in expression of both types I and III IFNs in human and mouse cell lines. We also show that Med23 knockout cells undergo genetic compensation, suggesting a critical role for MED23 in this pathway. Mechanistically, we show …
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From Flies to Mice: Drosophila as a Model System to Study Fat Biology
… inhibits PPARgamma function by directly binding Med23, a component of the Mediator Complex, which connects transcription factors with RNA polymerase II. Taken together, I have shown that both the Hh and Adp pathway have evolutionary conserved functions in fat formation. These results support the …