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Showing 1 to 17 of 17 for “"MED/08 Anatomia patologica"”.
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Profilo molecolare dei linfomi post-trapianto
Fifty-two cases of monomorphic post-transplant lymphoproliferative disorders (M-PTLD), developed in patients undergone solid organ or bone marrow transplantation, were studied by the application of the tissue micro-array (TMA) technology. They included 50 cases of diffuse large B-cell lymphomas …
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STUDIO DELLE BASI GENETICHE NELLA SINDROME DELLA MORTE IMPROVVISA DEL LATTANTE (SIDS) E NELLA MORTE INASPETTATA DEL FETO (SIUD)
… states the development of research programmes aimed to the reduction of the unexpected fetal death and the sudden infant death syndrome, that represent a major socio-medical problem. Currently, the literature doesn’t present in-depth investigations regarding the genetic bases of these …
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ESPRESSIONE DI SEL1L NEL CARCINOMA MAMMARIO - CORRELAZIONI CLINICO PATOLOGICHE
Malignant cells exhibit an exceptional ability to maintain homeostasis in an hostile environment, upregulation of proteins involved in the stress response with an increase in the apoptosis resistance, and in diminishing cell senescence or permanent arrest of cell division. SEL1L is a member of …
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Analisi genetico-molecolare dei linfomi a cellule T periferiche
… by poorer prognosis. In this study, we aimed to investigate the possible role in PTCL/NOS pathogenesis of selected molecules, known to be relevant for proliferation control. In particular, we analyzed the cell cycle regulators PTEN and CDKN1B/p27, the NF-kB pathway, and the tyrosin kinase …
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TRYPTOPHAN-DERIVED MICROBIAL METABOLITES PROMOTE NKT22 PRO-TUMORIGENIC FUNCTIONS IN COLITIS ASSOCIATED COLORECTAL CANCER PATIENTS
… via AhR activation. Metabolomic analysis confirmed elevated tryptophan metabolites in Odoribacter supernatants, driving NKT22 differentiation in vitro and in vivo. Administration of Odoribacter supernatant or purified metabolites enhanced tumorigenesis in CAC mouse models, but not in …
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RILIEVO DI FATTORI XENOBIOTICI, CON PARTICOLARE RIFERIMENTO A NICOTINA E COTININA, IN CAMPIONI ISTOLOGICI APPARTENENTI A FETI E NEONATI DECEDUTI PER CAUSE NATURALI.
RESEARCH OF XENOBIOTIC FACTORS, ESPECIALLY OF NICOTINE E COTININE, ON HISTOLOGICAL SAMPLES COLLECTED FROM FETUSES AND NEWBORNS DEAD FOR NATURAL CAUSES. As Sudden Infant Death Syndrome still holds many unknown etiopathogenetic aspects and as analytic chemical instruments and methods have appreciably …
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EXPRESSION OF SUBSTANCE P IN BRAINSTEMS OF VICTIMS OF SUDDEN UNEXPLAINED PERINATAL DEATH
Sudden perinatal death including SIDS is a rare but lethal syndrome and there is no symptom of this disorder until the fatal outcome has occurred. Epidemiological, genetic, molecular and pathological studies conducted so far give us some possible explanations about it but are inadequate to explain …
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BREAST CANCER DURING PREGNANCY AS A SPECIAL TYPE OF EARLY-ONSET BREAST CANCER: INSIGHTS INTO THE TUMOR MICROENVIRONMENT AND IMMUNE TRANSCRIPTOME
… CD4, CD8, forkhead box P3 (FOXP3), and programmed death-ligand 1 (PD-L1) (clone 22C3). A subset of 28 PrBC and 23 EOBC was selected for transcriptome profiling. RNA extracted from tumor (T) and corresponding normal (N) tissues was subjected to gene expression analysis using a next-generation …