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Showing 1 to 1 of 1 for “"MDM inhibition"”.

  1. Activation of the p53 pathway in combination with photon irradiation for the treatment of neurological tumour cells

    … study investigated the biological effects of the MDM2 inhibitor AMG232 in combination with photon irradiation in TP53- wild-type and TP53-mutant MB and GB cell lines, with the aim of assessing whether AMG232 enhances radiosensitivity in a TP53-dependent manner. Cell proliferation, cell-cycle …

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