Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"MDA-231"”.
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Role of TRAF2/6 in tumour growth and bone metastases associated with breast cancer
… highly metastatic bone-tropic clone of the human MDA-MB-231-BT (MDA-231-BT) breast cancer cells when compared to parental MDA-MB-231 (MDA-231) cells. Targeted knockdown of TRAF2, but not TRAF6, in both parental MDA-231 and bone-tropic MDA-231-BT breast cancer cells by siRNAs markedly reduced cell …
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Ο ρόλος της θρομβίνης και των υποδοχέων της στην αγγειογένεση και στην ανάπτυξη και μετάσταση του καρκίνου
… και LNCaP και στις σειρές από καρκίνο του μαστού MDA-231 και MCF-7. Η διερεύνηση της λειτουργικότητας του παραπάνω υποδοχέα στις προαναφερθείσες σειρές και το αποτέλεσμα της αναστολής του υποδοχέα στην επιβίωση και στον πολλαπλασιασμό των μελετώμενων κυττάρων. Η διερεύνηση της ενεργοποίησης της …
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The role of BCLFA1 in cellular transformation
… cell line (HeLa), breast cancer cell line (MDA-231) and two oesophageal cancer cell lines (KYSE30 and WHCO1), with a highly significant reduction in the breast cancer cell line (MDA-231). siRNA mediated knockdown of BCLAF1 resulted in altered expression of several downstream genes including …
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Compuestos homo y heterometalicos del grupo 11 con ligandos tipo terpiridina: Estudio de propiedades ópticas y biológicas
… Jurkat (leucemia), HT-29 (cancer de colon), MDA-231 (cancer de mama sin receptores hormonales) MC-F7 (cancer de mama con receptores hormonales), y además alguno de ellos ha resultado ser selectivo frente a celulas sanas (linfocitos T).
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Molecular Determinants of Tumor Re-Initiation in Breast Cancer
… (ER-negative) breast cancer cell lines, MDA-231 and CN34, were subjected to in vivo selection to yield 'tumorigenic-enriched' (TE) derivatives, which demonstrated enhanced tumor re-initiation capacity in multiple organ sites in a xenograft model. In the second part of this study, a …
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A Microfluidic Tissue Array (µFTA) For Personalized Medicine using Tumor Biopsies
… from cell-derived xenografts (CDX, e.g. MB-MDA-231 and BT 474) and patient-derived xenografts (PDX, e.g. M37 and M156) breast cancer models. As this work was in progress, other labs have also worked on creating a whole tissue culture system, but employ very low-throughput systems or systems …
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A Mutated Peptide Database for the Analysis of Proteomic Mass Spectrometry Data
… database was used to identify mutations in the MDA-MB-231 triple negative breast cancer cell line. A total of 540 unique mutations were identified, of which 60 were also part of the COSMIC's Cancer Gene Census database that incorporates genes implicated in cancer development through their …
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Synthesis of Novel CYP1 Activated Heterocyclic Anticancer Prodrugs
… or inducible CYP1 expression. These were the MDA 468, MCF7 and MDA 231 cell lines. The non-tumour MCF10A cell line which has no basal CYP1 expression was used as the control. A library of eighteen 3,5-diarylpyrazoles were synthesised. The lead pyrazole DMU 10107 …