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Showing 1 to 20 of 29 for “"MCTS"”.

  1. MONTE CARLO TREE SEARCH AND MINIMAX COMBINATION – APPLICATION OF SOLVING PROBLEMS IN THE GAME OF GO

    Monte Carlo Tree Search (MCTS) has been successfully applied to a variety of games. Its best-first algorithm enables implementations without evaluation functions. Combined with Upper Confidence bounds applied to Trees (UCT), MCTS has an advantage over traditional depth-limited minimax search with …

    maryland Repository record for MONTE CARLO TREE SEARCH AND MINIMAX COMBINATION – APPLICATION OF SOLVING PROBLEMS IN THE GAME OF GO (opens in a new tab)

  2. KIT Mutations in Australian Canine Mast Cell Tumours and Correlations with Patient Prognostic Factors

    … Receptor Tyrosine Kinase gene, KIT. Dogs with MCTs harbouring an internal tandem duplication (ITD) within exon 11 of the extracellular regulatory domain of KIT are more likely to respond to treatment with tyrosine kinase inhibitors. Conversely, MCTs with mutation of the intracellular tyrosine …

    adelaide Repository record for KIT Mutations in Australian Canine Mast Cell Tumours and Correlations with Patient Prognostic Factors (opens in a new tab)

  3. Towards Better Turn-Based Strategy Planning Agents: Turn-Based Evolutionary Tree Search

    … algorithms like Monte Carlo Tree Search (MCTS) and Rolling Horizon Evolutionary Algorithms (RHEA) struggle to scale. First, we perform an investigation into state-of-the-art Deep Learning based models for game agents in TUBSTAP. Then, we propose Turn-Based Evolutionary Tree Search (TBETS), …

    vt Repository record for Towards Better Turn-Based Strategy Planning Agents: Turn-Based Evolutionary Tree Search (opens in a new tab)

  4. An Intent-based Neural Monte Carlo Tree Search Framework for Synthesis of Printed Circuit Boards

    … proposes the usage of Monte Carlo Tree Search (MCTS) augmented to improve search in order to self-generate datasets, culminating in a process called LFS (Learning Feedback System). This process allows using past data to accelerate MCTS with deep RL models on new or similar board configurations. …

    mit Repository record for An Intent-based Neural Monte Carlo Tree Search Framework for Synthesis of Printed Circuit Boards (opens in a new tab)

  5. Simulation-Based General Game Playing

    … this challenge with Monte-Carlo Tree Search (MCTS), which in recent years has become a popular and effective search method in games. For competitive play such an approach requires an effective search-control mechanism for guiding the simulation playouts. In here we describe our GGP agent, …

    reykjavik Repository record for Simulation-Based General Game Playing (opens in a new tab)

  6. Differential membrane-type matrix metalloproteinase expression in phenotypically defined breast cancer cell lines: Comparison of MT-MMP expression in environmentally-challenged 2D monolayer cultures and 3D multicellular tumour spheroids

    … confirm that 3D multicellular tumour spheroids (MCTS) using phenotype-specific breast cancer cell lines are a valuable experimental model of the tumour microenvironment. Optimisation of MCTS culture growth conditions using different breast cancer cell lines (MCF-7, T47D, MDA-MB-468 and …

    bradford Repository record for Differential membrane-type matrix metalloproteinase expression in phenotypically defined breast cancer cell lines: Comparison of MT-MMP expression in environmentally-challenged 2D monolayer cultures and 3D multicellular tumour spheroids (opens in a new tab)

  7. Correlation of HAS2-associated gene duplications with biological aggressiveness of mast cell tumors in Chinese Shar-Pei dogs

    … in Shar-Pei dogs. Biopsies of cutaneous MCTs from 149 Shar-Pei and 100 non-Shar-Pei were graded according to two schemes for canine cutaneous MCTs. Biopsies of the Shar-Pei MCTs were also evaluated for degree of cutaneous mucinosis, depth of invasion, and microvessel density (MVD). …

    colostate Repository record for Correlation of HAS2-associated gene duplications with biological aggressiveness of mast cell tumors in Chinese Shar-Pei dogs (opens in a new tab)

  8. The use of optical coherence tomography to enhance surgical margin assessment for canine mast cell tumors

    … margins (SM) of excised mast cell tumors (MCTs). Secondly, to determine the feasibility and utility of OCT imaging to direct pathological sectioning of resected MCTs. Study design: Prospective, ex vivo study Animals: 15 dogs with 22 MCTs Methods: MCTs were excised, and a specific …

    uiuc Repository record for The use of optical coherence tomography to enhance surgical margin assessment for canine mast cell tumors (opens in a new tab)

  9. Design-technology Co-optimization for Sub-2 nm Technology Node Based on 2D Materials

    … of MoS₂-based multichannel transistors (MCTs). With the help of DTCO, we have achieved record performance for double-gate, single-channel MoS₂ transistors as well as the first demonstration of high-performance, functional double channel MoS₂ transistors. Based on the results of MCTs, a …

    mit Repository record for Design-technology Co-optimization for Sub-2 nm Technology Node Based on 2D Materials (opens in a new tab)

  10. The role of the tumour microenvironment components in cancer cell behaviour and drug response

    … this study utilized multi-cell tumour spheroids (MCTS) from WHCO1 and MDA MB 231 cells co-cultured with WI38 and CT1 fibroblasts to mimic tumour cell-stromal cell interactions as observed within the in vivo tumour microenvironment. The data show that spheroids were more resistant to drugs than …

    cape-town Repository record for The role of the tumour microenvironment components in cancer cell behaviour and drug response (opens in a new tab)

  11. Unsupervised Relation Extraction for E-Learning Applications

    … growth for e-Learning. Multiple Choice Tests (MCTs) are a popular form of assessment and are quite frequently used by many e-Learning applications as they are well adapted to assessing factual, conceptual and procedural information. In this thesis, we present an alternative to the lengthy and …

    wlv Repository record for Unsupervised Relation Extraction for E-Learning Applications (opens in a new tab)

  12. Advancement in In-Silico Drug Discovery from Virtual Screening Molecular Dockings to De-Novo Drug Design Transformer-based Generative AI and Reinforcement Learning

    … algorithms like Monte Carlo Tree Search (MCTS), these systems can optimize the generated molecules for desired properties, such as binding affinity, specificity, and pharmacokinetics.</p> <p>An exemplary study in this domain involved the design of novel inhibitors for the COVID-19 Mpro …

    chapman Repository record for Advancement in In-Silico Drug Discovery from Virtual Screening Molecular Dockings to De-Novo Drug Design Transformer-based Generative AI and Reinforcement Learning (opens in a new tab)

  13. Data Efficient Reinforcement Learning

    … use of simulation-based Monte Carlo Tree Search (MCTS) in RL, as exemplified by the remarkable achievement of AlphaGo Zero, and probe the data efficiency of incorporating such a key ingredient. Specifically, we investigate the correct form to utilize such a tree structure for estimating values and …

    mit Repository record for Data Efficient Reinforcement Learning (opens in a new tab)

  14. New algorithmic developments in maximum consensus robust fitting

    … of LP-type problems and Monte Carlo Tree Search (MCTS). The proposed algorithm relies on a fundamental geometric arrangement of the data to guide the sampling process. Specifically, we take advantage of the underlying tree structure of the maximum consensus problem and apply MCTS to efficiently …

    adelaide Repository record for New algorithmic developments in maximum consensus robust fitting (opens in a new tab)

  15. Optimising Agent Behaviours and Game Parameters to Meet Designer’s Objectives

    … problems. It also demonstrates the adaptivity of MCTS NPC which uses the evaluation method. This NPC performs reasonably well given adequate resources and no reference NPC is required.

    essex Repository record for Optimising Agent Behaviours and Game Parameters to Meet Designer’s Objectives (opens in a new tab)

  16. Evolutionary Design of Game Vehicles and Their Controllers

    … controllers, simple rule-based controllers, and MCTS-based controllers as means to test and therefore indirectly guide the evolution of vehicle designs. We are able to demonstrate that evolutionary algorithms can be used to generate effective vehicle designs, suitable for use by the same …

    essex Repository record for Evolutionary Design of Game Vehicles and Their Controllers (opens in a new tab)

  17. Postmortem metabolism in porcine skeletal muscle

    … proton-linked iii monocarboxylate transporters (MCTs). Previous reports indicated that acute activation of AMPK increased monocarboxylate transporter expression in skeletal muscle of other species. Yet, it was unknown the impact chronic activation of AMPK will have on MCT1, MCT2, and MCT4 …

    vt Repository record for Postmortem metabolism in porcine skeletal muscle (opens in a new tab)

  18. Development and Intratumoral Distribution of Block Copolymer Micelles as Nanomedicines for the Targeted Delivery of Chemotherapy to Solid Tumors

    … rate. The use of multicellular tumor spheroids (MCTS) was established as a viable platform for assessing the efficacy and tumor tissue penetration of nanomedicines in vitro. A series of complementary assays was validated for analysis of DTX-loaded micelle (BCM+DTX) toxicity in monolayer and …

    toronto-retro Repository record for Development and Intratumoral Distribution of Block Copolymer Micelles as Nanomedicines for the Targeted Delivery of Chemotherapy to Solid Tumors (opens in a new tab)

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