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Showing 1 to 20 of 108 for “"MCP-1"”.
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High Fat Diet Effects on Erythrophagocytosis and MCP-1 Levels in Mice
… murine RBC monocyte chemoattractant protein 1 (MCP-1) content and ex vivo murine macrophage erythrophagocytosis levels.</p><p>Methods: 6 week old C57BL/6 male mice were fed either chow diet (CD) as control (n=8) or a HFD (n=8) for 12 weeks. Body mass was measured upon arrival and at 18 weeks of …
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Mcp-1 Release Modulation Through Interaction of Pulmonary Endothelial Cells and Mesenchymal Stromal Cells
… Monocyte Chemoattractant Protein - 1 (MCP-1), is an important</p> <p>chemokine involved in the recruitment of monocytes and macrophages. In our study,</p> <p>we wanted to explore the interactions between MSCs with PECs and how this</p> <p>interaction changes the expression levels of …
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Die Bedeutung von Monocyte Chemotactic Protein - 1 (MCP - 1) für die Angiogenese des Glioms
… Angio- und Venogenese experimenteller MCP-1 produzierenden CNS-1 Rattengliomzellen mittels CAM-Assays von Gallus gallus domesticus und Coturnix coturnix japonica. Histologische Schnitt- und Färbetechniken zeigen die Gefäßdifferenzierung der MCP-1-Gliome übertraf deutlich das der …
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Die Rolle des Tumorsuppressors p53 für die TNF-alpha-vermittelte Induktion des MCP-1-Gens
… Das "Monocyte-Chemoattractant-Protein-1" (MCP-1/CCL2) ist ein wichtiges Mitglied der Chemokin-Familie und löst die Infiltration von Monozyten/Makrophagen aus. Die Expression von MCP-1 tritt bei verschiedenen Krankheiten, die durch den Einstrom von Monozyten charakterisiert sind, auf. Es …
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MCP-1, Macrophages and Tumorigenesis in the C3(1)/Sv40Tag Mouse Model of Breast Cancer: Benefits of Quercetin
… is associated with enhanced BrCa risk. MCP-1 is an important chemoattractant released from the tumor microenvironment that contributes to the accumulation of tumor associated macrophages (TAMs). TAMs enhance mammary tumor growth by promoting chronic inflammation, tumor cell invasion, …
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Effekte von Leptin- und MCP-1-Applikation auf funktionelle Parameter der Arteriogenese : eine experimentelle Studie mittels Ultraschallflussmessungen, Mikrosphärperfusion und Proliferationsanalyse
… darstellt. Ein bekanntes arteriogenes Zytokin, MCP-1 (monocyte chemoattractant protein-1) wurde mit dem Adipozytokin Leptin, das bisher nicht hinsichtlich seiner Wirkung auf das Kollateralarterienwachstum <br>untersucht war, verglichen. Zur Validierung des Gefäßwachstums wurden …
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Using urinary MCP-1 and TWEAK to assess disease activity in a cohort of South African patients with lupus nephritis
… biomarkers. Monocyte chemoattractant protein-1 (MCP-1) and tumour necrosis factor-like weak inducer of apoptosis (TWEAK) have been implicated in the pathogenesis of LN and are thus potential biomarkers for disease activity monitoring. Methods: In this study urinary MCP-1 (uMCP-1) and TWEAK …
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Exposure of 3D organotypic vaginal tissues to semen induces expression of the chemokine MCP-1, but does not alter tissue integrity
… did significantly upregulate the expression of MCP-1, a chemokine that can attract HIV target cells such as CD4+ T cells and macrophages. We believe this research closes an important gap in understanding the impact of semen on vaginal epithelium cells by showing that semen does not have a broad …
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Correlation of urinary mcp-1 and tweak with renal histology and early response to therapy in newly biopsied patients with lupus nephritis in cape town, South Africa
… such as monocyte chemoattractant protein-1 (MCP-1) and tumour necrosis factor-like weak inducer of apoptosis (TWEAK) are secreted in the kidney and may be useful for predicting histological class, monitoring flares and assessing response to therapy. We assessed the utility of urinary MCP-1 …
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Effect of Cysteinyl Leukotriene D4 on Chemokine Expression via Cysteinyl Leukotriene Receptor 1 in Human Lung Epithelial Cells, A549
… cysteinyl leukotriene receptor 1(CysLTR1). CCL2 (MCP-1, Monocyte Chemoattractant protein-1) is one of the major chemokines responsible for attracting monocytes. CXCL10 (IP-10, IFN-γ-inducible protein 10kDa) is an IFN-γ-inducible chemokine that preferentially attracts activated Th1 lymphocytes. …
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The Role of Monocyte Chemotactic Protein-1 In the Development of Central Nervous System Fatigue In Healthy Mice and In Response to Cancer Chemotherapy
… possible role of monocyte chemotactic protein-1 (MCP-1) in the occurrence of fatigue, especially in fatigue associated with cancer and cancer chemotherapy treatments, known as cancer-related fatigue (CRF). Moreover, accumulating evidence shows that peripheral MCP-1 expression is increased with …
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Characterization and application of adipose derived stem cells following burn injury
… controls. Monocyte chemo-attractant protein-1 (MCP-1) mRNA expression was also greater with ASC treatment (p< 0.05). ASCs secreted a significant amount of MCP-1 compared to the different cell lines when challenged with lipopolysaccharide (LPS) or 2% burn serum. Human umbilical vein endothelial …
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Die Bedeutung leukozytärer Subpopulationen für die Arteriogenese im Kaninchenhinterlauf
… von Monozyten durch spezifische Zytokine (MCP-1, TGF-ß) vermag die Entwicklung von Kollateralarterien nach Gefäßokklusion (Arteriogenese) signifikant zu beschleunigen. Diese Substanzen wirken jedoch nicht nur auf Monozyten, und die Beteiligung anderer Leukozytensubpopulationen mit bekannter …
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Mechanism of local IL-6 production and its role in accelerating vascular inflammation leading to aortic diseases
… into aged C57BL/6J mice induced aortic IL-6 and MCP-1 predominantly in the tunica adventitia. Likewise, IL-6 was detected mostly in the adventitia of sporadic aortic dissections in humans. There was concomitant macrophage recruitment, adventitial expansion, and development of thoracic and …
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Statin-Mediated Attenuation of Chemokine Expression in Peripheral Nerve Vascular Endothelial Cells
… that TNF-α, monocyte chemoattractant protein-1 (MCP-1), and intercellular adhesion molecule-1 (ICAM-1) are locally increased in patients with GBS, correlating with disease severity. Similar findings have been demonstrated in an animal model of GBS, experimental autoimmune neuritis …
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Local Inflammatory Responses in Pseudomyxoma Peritonei
… 10 (IP-10) and monocyte chemotactic protein 1 (MCP-1). Effects of IL-6 and IL-8 on cell growth were determined using recombinant human cytokines and the human mucinous colorectal cell line, LS174T (a surrogate for PMP cells).|The levels (median, range) of pg/ml of IL-6 (2493, 17.7-9267.97), IL-8 …
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Investigation of chemokine expression and modulation following traumatic brain injury
… chemokine, monocyte chemoattractant protein-1 (MCP-1/CCL2) are derived from glial. However the origin of these chemokines following TBI, has not been established. Furthermore, little is known about the modulation of these chemokines: The relationship of serum levels of pro-inflammatory mediators …
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Effects of 5-Fluorouracil Chemotherapy On Fatigue and Inflammation In Mice: Benefits of Quercetin
… post (p<0.05). In the 40 mg/kg dose, IL-6 and MCP-1 were slightly elevated in the cortex at 5 and 14 days, respectively, but were not elevated in the 60 mg/kg dose. However, MCP-1 was significantly elevated in the plasma in the 60 mg/kg dose. To confirm to role of MCP-1, the voluntary activity …
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A Study on the Effect of Peroxisome Proliferator-Activated Receptors (PPARs) Activation in Cultured Rat Brain Glial Cells
… (IL-1？) and monocyte chemoattractant proteins (MCP-1) through suppressing activation of STAT1. Along with LPS, we further investigated whether activators of PPAR-？ and -？ also suppressed expression of pro-inflammatory mediators in IFN-？-activated rat astrocytes. Activators of PPAR-？ inhibited …
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