Global ETD Search
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Showing 1 to 3 of 3 for “"MCHR-1"”.
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Melanin-Concentrating Hormone Receptor-1 is Enriched in Lipid Rafts and the Effects of Lipid Raft Integrity on Receptor Signaling
The melanin-concentrating hormone receptor-1 (MCHR-1) is a member of the G protein-coupled receptor (GPCR) superfamily, and functions in the regulation of food consumption and energy metabolism. MCHR-1 is expressed in neural, pancreatic, and fat tissue. Fat cells begin their journey as …
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Neurochemical and functional characterisation of the Melanin-concentrating hormone system in the rat brain
… hormone receptor subtype 1 (MCHR-1) knock-out animals. The anorectic and anti-obesity effects of selective MCHR-1 antagonists have confirmed the notion that pharmacological blockade of MCHR-1 is a potential therapeutic approach for obesity. First aim of this work is to study …
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The Identification of the MCHR-1 in J774A.1 Macrophages and The Effect of Melanin-concentrating Hormone on a 3T3-L1 Adipocyte-J774A.1 Macrophage Co-Culture
… whether theses J774A.1 macrophage expressed the Mchr1 gene and MCH receptor protein as well as whether this cell line responded at all to MCH. Finally, migration was quantified via fluorescein-labeled macrophages into a pre-adipocyte culture with and without MCH treatment in a co-culture. These …