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Showing 1 to 2 of 2 for “"MC160 Protein"”.
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Characterization of the Anti-Inflammatory Effects of the Molluscum Contagiosum Virus MC160 Protein
Using a series of MC160 deletion mutant proteins, we found that two distinct regions of the MC160 protein independently inhibit TNF-mediated NF-kappaB activation. Specifically, we observed that the second DED of MC160 interacts with procaspase-8 as a means to inhibit NF-kappaB activation, while the …
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Functional Analysis of the Molluscum Contagiosum Virus MC160 Death Effector Domain-Containing Protein RxDL Motif
… two death effector domain (DED) containing proteins, MC159 and MC160. DEDs are found in cellular proteins such as FADD and procaspase-8. These cellular proteins are involved in several innate immune responses such as apoptosis and activation of interferon (IFN). Presumably, MC159 and MC160 …