Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 52 for “"MBD"”.
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Scale-Up the Use of a Microbubble Dispersion to Increase Oxygen Transfer in Aerobic Fermentation of Baker's Yeast
A microbubble dispersion (MBD) was used to supply oxygen for an aerobic fermentation of Baker's yeast. The 1-liter microbubble dispersion generator supplied bubbles for 20-liter and 50-liter working volume fermentations in a 72-liter pilot scale fermenter. The microbubbles were stabilized by the …
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Microbubble fermentation of recombinant Pichia pastoris for human serum albumin production
… of 350, 500, and 750 rpm, and were compared to MBD sparged fermentation at 150, 350, and 500 rpm agitation rates. The MBD improved the volumetric oxygen transfer coefficient (kLa) and subsequently increased the cell mass and protein production compared to conventional fermentation. Cell …
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Effects of inulin supplementation on markers of mineral and bone metabolism and the gut microbiota in hemodialysis patients
… have some degree of mineral and bone disorder (MBD), which is associated with higher morbidity and mortality, specifically from cardiovascular causes. Despite the pharmacological treatment for MBD, its prevalence remains high, especially for patients with kidney failure undergoing chronic …
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Utilization of a Microbubble Dispersion to Increase Oxygen Transfer in Pilot-Scale Baker's Yeast Fermentation Unit
… power consumption. A microbubble dispersion (MBD) method was investigated to improve oxygen transfer at low agitation rates and thus reduce power consumption and shear stress on the microorganisms. The experiments were conducted at the 1-liter level and subsequently scaled-up to 50-liters …
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A Novel Approach for the Visualisation and Progression Tracking of Metastatic Bone Disease
Metastatic bone disease (MBD) is a common secondary feature of cancer that can cause significant complications, including severe pain and death. Current methods of diagnosis require a highly trained radiologist capable of interpreting medical images and recognising the sites of MBD. These medical …
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DNA methylation detection using an engineered methyl-CpG-binding protein
… to more patients. Methyl-CpG-binding domain (MBD) proteins bind specifically to methylated DNA sequences, and many assays have been developed that use these proteins in methylation profiling of DNA. The wild-type proteins in the MBD family bind specifically to symmetrically methylated CpG …
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Rapid Prototyping of Software Defined Radios using Model Based Design for FPGAs
… can be improved using Model based design (MBD) tools. These tools encourage a modular way of developing waveforms for radios. The tools based on MBD have been the focus of recent research exploring the concept of the platform independent model (PIM) and portability across platforms by the …
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Increased oxygen transfer in a yeast fermentation using a microbubble dispersion
The use of a microbubble dispersion (MBD) for oxygen transport in a yeast fermentation was studied. No surfactants were added to the fermentations; the microbubbles were formed using only the surfactants naturally produced by the yeast. The growth rate of a Saccharomyces cerevisiae culture was …
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The electrochemistry of phenothiazine derivatives
Methylene blue derivatives (MBDs) such as methylene blue (MB -), 1-methyl methylene blue (1MMB) and 1,9-dimethyl-methylene blue (DMMB) have potential use as drugs within photodynamic therapy (PDT). Knowing the redox properties of MBDs will help in understanding the way in which MBDs interact with a …
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Crystallographic studies of the metal-responsive transcription factor NikR
… regulatory domain that binds metal ions (MBD). NikR is the only known metal- responsive member of the RHH family of transcription factors, and the structural relationships between NikR and other RHH proteins are detailed in this thesis. The high- affinity nickel-binding site of NikR is …
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Improving Care Coordination for Children with Autism Spectrum Disorders and Developmental Disorders/Delay/Disabilities in the United States
… examined PCMH utilization across both ASD/DD and MBD. The specific questions posed in this dissertation provide insights into status of current CC through Patient Centered Medical Home (PCMH) and its association with ED visits, urban and rural differences on PCMH utilization, and healthcare …
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Methylated DNA detection using a high-affinity methyl-CpG binding protein and photopolymerization-based amplification
… analysis in the clinic. Methyl binding domain (MBD) family proteins specifically bind double-stranded, methylated DNA which makes them excellent transducers for DNA methylation in biosensing applications. I displayed three of the core members MBD1, MBD2, and MBD4 on the surface of Saccharomyces …
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Relating metal binding to DNA binding in the nickel regulatory protein NikR
… factor with a central metal binding domain (MBD) that includes the tetrameric interface and two flanking dimeric ribbon-helix-helix (RHH) DNA-binding domains. Early work revealed that NikR can bind a variety of transition metal ions and has two binding affinities for the nik operon: nM when …
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Second Language Vocabulary Learning in the Digital Era A Study of Mobile-based Dictionaries (MBDs) in Chinese EFL Learners’ Incidental English Vocabulary Learning: Exploring Effectiveness, Learners’ Use and Attitude
… to increasing use of mobile-based dictionaries (MBDs) by English as a Foreign Language (EFL) learners at Chinese universities, especially for self-directed informal language learning. Although many studies have explored the role of dictionaries in Chinese learners’ L2 vocabulary learning, few …
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Secure SNMP-Based Network Management in Low Bandwidth Networks
… is based on the Management by Delegation (MbD) model and is implemented using the IETF DISMAN Script MIB. This research demonstrates that the MbD-based management framework consumes only 2 percent of the network capacity required by the traditional, centralized management scheme.
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Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development
… isoforms containing the Moesin Binding Domain (MBD), we found that isoforms lacking the MBD also function in actin remodeling. Consistent with this, we found that the C-terminal half of BtszB cooperatively bound and bundled F-actin with micromolar affinity, suggesting a direct mechanism for …
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Visual saliency computation for image analysis
… between BMS and the Minimum Barrier Distance (MBD) transform to provide insight into our algorithm. Experiment results show that BMS compares favorably with state-of-the-art methods on seven benchmark datasets. 2) Salient Region Detection. Salient region detection entails computing a saliency …
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Reconfigurable modelling of physically based systems: Dynamic modelling and optimisation for product design and development applied to the automotive drivetrain system.
… environments making use of Model Based Design (¿MBD¿) and similar procedures. A review of model development and use forms the foundation of the work, with the findings being aggregated into two unique approaches for rapid model development and reconfiguration; the Plug-and-Simulate (¿PaS¿) …
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Using a Porcine Maternal Infanticide Model to Investigate the Inheritance of Human Puerperal Psychosis
… model. In the second, the author has created MBD-Seq libraries from archival tissue, and then performed differential methylation analysis. The results indicated that it is possible to use MBD-Seq technologies with Sus scrofa brain tissue. Once again, the effect of confounding factors and …
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Fast scanning two-photon microscopy
… to the neuron cell body was tested using a ChR2-MBD construct.
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