Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 66 for “"MAVs"”.
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Measurement of aerodynamic characteristics of MAVs using motion tracking
… characteristics of Micro Air Vehicles (MAVs) is not well addressed in aeronautics literature, and more experimental data are required to help better understand the behavior of fixed-wing MAVs. In the current research, aerodynamic and stability characteristics of two MAVs were measured …
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Structural Basis for the Activation of RIG-I/MAVS Antiviral Immune Signaling
The file named "XU-DISSERTATION-2015.pdf" is the primary dissertation file. The supplemental file named "Movie 1.mp4" may be viewed individually.
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COCAINE AND HIV-1 REGULATE ASTROCYTE MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN (MAVS) MEDIATED INFLAMMATION
… mitochondrial antiviral signaling protein (MAVS) mediates the mechanism by which cocaine induces antiviral responses. MAVS is a vital part of our innate immune system that responds to viral perturbation, chemical hypoxia, host cell injury and metabolic perturbations. We investigated the role …
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Roles of MAVs and MYD88 in Innate and Adaptive Immune Responses to Respiratory Syncytial Virus
… TRIF (TLR3, 4), MyD88 (TLR4, 7/8, 9), and MAVS (RIG-I). The innate response serves to limit viral spread and to activate adaptive immune responses which eventually clear the infection. We dissected the contribution of TLR- and RLR- mediated recognition in the host response to Respiratory …
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Characterization of The Roles of Carma3 and Bcl10 In Virus-Triggered Rig-I/Mavs Signaling Pathway
… cytokines by mitochondrial protein MAVS, which forms a prion-like structure to recruit TBK1and IKK complex to activate IRF3 and NF-κB, respectively. Herein, we revealed the important roles of CARMA3 and BCL10 in RIG-I/MAVS signaling pathway for the first time. CARMA3 or BCL10 …
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The Adar-Mavs Pathway Is A Critical Mediator of The Innate Immune System In Pancreatic Development and Cancer
… is to prevent aberrant activation of the Mavs-mediated innate immune pathway, thereby maintaining pancreatic homeostasis. Pancreatic cancer has a desmoplastic stroma and most immune checkpoint blockade therapies fail to restrict it. Almost 18% of pancreatic cancer patient tumors have an …
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Modeling, Designing, Building, and Testing a Microtubular Fuel Cell Stack Power Supply System for Micro Air Vehicle (MAVs)
… cell stack system for micro aerial vehicles (MAVs) was conducted by Virginia Tech in collaboration with Luna Innovations, Inc, in an effort to replace the lithium battery technology currently powering these devices. Investigation of planar proton exchange membrane (PEM) and direct methanol …
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바이러스 감염시 미토콘드리아 E3 ubiquitin ligase 인 MARCH5의 새로운 생체 기능
… First, the mitochondrial antiviral signaling (MAVS) protein forms aggregates that elicit robust type-I interferon induction on viral infection, but persistent MAVS signaling leads to host immunopathology; it remains unknown how these signaling aggregates are resolved. Here I identify the …
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Cooperative Control of Miniature Air Vehicles
Cooperative control for miniature air vehicles (MAVs) is currently a highly researched topic. There are many application for which MAVs are well suited, including fire monitoring, surveillance and reconaissance, and search and rescue missions. All of these applications can be carried out more …
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Understanding Host Antiviral Signaling Pathways
… of a CARD domain containing protein, termed MAVS (Mitochondrial AntiViral Signaling protein) that functions downstream of RIG-I in the antiviral signaling pathway. Besides the N-terminal CARD domain, MAVS also contains a hydrophobic C-terminal transmembrane domain that targets the protein to …
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Visualisation of innate immune signalling complexes in cells by cryo-electron tomography
… the mitochondrial antiviral- signalling protein (MAVS) on the outer mitochondrial membrane. MAVS signalling induces activation of cytosolic kinases, which in turn activates transcription factors IRF3 and NF-kB to promote interferon production. Similarly, activation of NLRP3, a sensor protein to …
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Scalable and Modular Manufacturing of Insect-Scale Aerial Robots Towards Swarm Flight Demonstrations
… feats, insect-scale micro aerial vehicles (MAVs) have been developed with advanced flight functionalities, including collision resilience and aerial acrobatics. Despite these advancements, MAVs weighing less than a gram continue to face critical challenges in design, assembly, and repair. …
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Key Role of Lys63-Linked Polyubiquitination in Viral Activation of IRF3
… for sensing intracellular viral RNAs. MAVS, a mitochondria-localized transmembrane protein, transduces signaling from RIG-I and MDA5 to activate downstream transcription factors IRF3 and NF-kB, which contribute to the induction of IFNb. Despite growing list of components revealed in …
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Predicting Drag Polars For Micro Air Vehicles
<p> Drag polars for three Micro Air Vehicles (MAVs) were measured at Reynolds numbers of 70,000, 50,000, 30,000, and 10,000 and compared to predictions generated using the classical approach. The MAVs tested had different configurations and aspect ratios varying from 1.2 to 1.6 and ratios of wetted …
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Micro air vehicle motion tracking and aerodynamic modeling
… of the aerodynamics of micro air vehicles (MAVs) flying at Reynolds numbers between 10,000 and 30,000. Experimental studies have shown the aerodynamic effects of low Reynolds number flow on wings and airfoils, but the amount of work that has been conducted is not extensive and mostly limited …
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Mechanism of Ubiquitin Induced Activation of RIG-I Like Receptors in Antiviral Innate Immunity
… known to mediate protein-protein interactions. MAVS also contain one CARD domain. It has been proposed that the activation of MAVS by RIG-I is mediated by homotypic interaction between their CARD domains. However, it is hard to detect stable interaction between the CARD domains of RIG-I and that …
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Evasion of RIG-I/MDA5 and TLR3-mediated innate immunity by hepatitis A virus
… induction of type I IFN through proteolysis of MAVS, a mitochondrial-localized adaptor of RIG-I and MDA5, by the viral 3ABC protease precursor. The 3ABC cleavage of MAVS requires both the protease activity of 3Cpro and a transmembrane domain in 3A that directs 3ABC to mitochondria. The signaling …
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Design, optimization and flight testing of a micro air vehicle
Micro Air Vehicles (MAVs) are a new type of aircraft maturing every year. The first mission-capable MAVs are already available on the market. Similarly to larger UAVs, MAVs may be used in a variety of applications, both military and civilian, such as situational awareness, reconnaissance, data …
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Control and estimation strategies for autonomous MAV landing on a moving platform in turbulent wind conditions
Micro aerial vehicles (MAVs) are increasing in popularity both for recreational and commercial purposes. In particular, autonomous MAVs are promising in the field of drone delivery due to their scalability, deployability, and low cost compared to traditional ground delivery. Hybrid systems, which …
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Algorithmic Aspects of Perception-Aware Motion Planning on Resource-Constrained Platforms
Autonomous micro aerial vehicles (MAVs) are becoming an integral tool in numerous applications involving time-critical missions in GPS-denied environments. Due to their small size and lean energy budget, MAVs are often equipped with a camera to aid ego-localization. This introduces at least two …
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