Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"MATE transporters"”.
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Using Dictyostelium discoideum to develop flavonoid therapeutics for polycystic kidney disease: the role of MATE transporters
… of two novel multidrug and toxin efflux (MATE) transporters. Their role in biological and biomedical implications of flavonoid transport in this model microbe are considered in the light of the evidence for naringenin specifically inhibiting cyst-forming kidney disease. D. discoideum is a …
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Energetics and Structural Aspects of Cation-Coupled Drug Transport by NorM Multidrug Transporters
… the multiple antibiotics and toxins extrusion (MATE) family of secondary active transporters. Members of this family are present across all species including bacteria, plants and humans. In bacteria, their over-expression can lead to antibiotic resistance, whereas in the human body, the …
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Dissection of Drought Responses in Arabidopsis
… They have therefore evolved mechanisms to acclimate and tolerate environmental stresses. Knowledge of the molecular aspects of abiotic stress gleaned from extensive studies in Arabidopsis has provided much information on the complex processes underlying plant response to abiotic stresses. …
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Phytochemical diversity and genetics of purple corn
… (ANR) associated with flavonol synthesis, and MATE transporters that may function in more efficient vacuolar sequestration of acylated anthocyanins. In addition to GWAS, GS was used to predict anthocyanin content in AR. Five-fold cross validation resulted in high prediction accuracies, …
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Deciphering Multidrug Efflux: Substrate Interactions and Transport Mechanisms in PatAB and NorM-VC
Multidrug efflux transporters are ubiquitously expressed in all kingdoms of life. In bacteria, they participate in several innate physiological functions to aid survival and adaptation. Given their crucial roles in conferring antimicrobial resistance (AMR), the understanding of the structural and …