Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"MARV"”.
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POST-EXPOSURE TREATMENT OF MARBURG VIRUS ANGOLA DISEASE IN NON-HUMAN PRIMATES USING RECOMBINANT VESICULAR STOMATITIS VIRUS VECTORS
… vaccines or treatments exist for Marburg virus (MARV) disease. As a preventative vaccine, a recombinant vesicular stomatitis virus (rVSV) expressing the Musoke strain glycoprotein (GP) of MARV protects macaques against MARV Musoke and Angola variants, as well as Ravn virus. The vector is also …
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Improved convergence for optimization of evasive maneuvering
… maneuvers for a Maneuvering Reentry Vehicle (MaRV) attacking a target defended with Anti-Ballistic Missiles (ABMs). The problem is large in terms of the number of optimization parameters, and perhaps in terms of the number of nonlinear constraints. Since both MaRV and ABM trajectories are …
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Elucidating the Immunogenicity and Protective Immune Response of a Trivalent Vaccine for Sudan Ebola, Marburg, and Lassa Fever Viruses
Sudan Ebola (SUDV), Marburg (MARV), and Lassa fever (LASV) viruses cause acute, severe haemorrhagic fevers resulting in high morbidity and mortality in overlapping regions of Africa. Despite millions of individuals in Africa being at risk of contracting an infection from one of these viruses, …
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Development of Small Molecules as Broad-spectrum Filoviral Entry Inhibitors
Ebola (EBOV) and Marburg (MARV) filoviruses are priority infectious agents due to their high pathogenicity and lethality in infected patients. The current lack of pan-filoviral therapeutics exemplifies the need for effective treatments against diverse filoviruses. The filoviral glycoprotein (GP) …
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Plans, pans, and six grand in the can
… territory. It was my experience in making "Marv Cutler and the Little Prince of Rock" that preconceptions in shooting a scene were rarely realized. The footage returned by the lab, having been shot by me in a state of instant surprise, often had a puzzle quality which would then be reworked …
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Discovering LC3-interacting region (LIR) motifs in hemorrhagic fever viruses: Implications for host autophagy and viral replication.
… between LC3 and the Marburg virus nucleoprotein (MARV NP). Utilizing isothermal titration calorimetry and co-immunoprecipitation we have confirmed the interaction of MARV NP and LCA via a LIR motif, and determined that the interaction modulates autophagy in cellulo, demonstrating the ability of …
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Aptamers that bind filovirus GP : a new frontier for detection and neutralization of Ebola and Marburg virus
… probes that differentially recognize GPs from MARV and EBOV. This work represents the first step in the development of aptamer based-low-cost point of care devices for filovirus disease diagnostics. Finally, this work describes the use of a hybrid selection approach that combines two different …