Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"MAPKKK"”.
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BTB-Kelch Proteins and TAk1 Kinase N Immune Function
… photosensitive organs. TAK1 is a member of MAPKKK. Deletion of TAK1 prevented the maturation of CD4+ or CD8+ single positive thymocytes, leading to reduction of T cells in peripheral tissues. Thymocytes lacking TAK1 failed to activate NF-κB and JNK, and were prone to apoptosis upon …
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Studies towards a fast and efficient total synthesis of LL-Z1640-2
… mitogen activated protein kinase kinase kinase (MAPKKK) family. TAK1 is responsible for the activation and control of at least three signalling pathways that play crucial roles in the inflammatory response. Hence, TAK1 has emerged as a prime target for the treatment and regulation of chronic …
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Endothelin-1 Induced Phosphorylation of ERK1/2 in Bovine Corneal Endothelial Cells
<p>The purpose of this study was to determine whether Endothelin-1 (ET-1) induced cellular responses in bovine corneal endothelial cells (BCECs) involves MAPK pathway by phosphorylating ERK1/2 protein kinase and to find out the phosphorylation patterns of ERK1/2 in confluent and sub-confluent …
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MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia
… a three-tiered kinase cascade comprising a MAPKKK, that can activate MAPKK, which in turn activates and phosphorylates MAPKs [170]. Activation of MAPK pathways regulates the activity of a number of transcription factors that are present in the cytoplasm or the cell nucleus, such as Elk-1, …