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Showing 1 to 3 of 3 for “"MAP Kinase Kinase Kinases"”.

  1. BTB-Kelch Proteins and TAk1 Kinase N Immune Function

    … photosensitive organs. TAK1 is a member of MAPKKK. Deletion of TAK1 prevented the maturation of CD4+ or CD8+ single positive thymocytes, leading to reduction of T cells in peripheral tissues. Thymocytes lacking TAK1 failed to activate NF-κB and JNK, and were prone to apoptosis upon …

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  2. Mechanism and Regulation of ERK2 Subcellular Localization

    … that regulated compartmentalization of the kinases and substrates may contribute to the fidelity of phenotypic changes in response to specific cell stimuli. Therefore, elucidating the mechanism of translocation as well as how this process is controlled is important for understanding how MAP

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  3. Identification of Intracellular Signaling Pathways Regulated by the TAO Family of Mammalian STE20p Kinases

    … 3 are a sub-family of mammalian Ste20p protein kinases. They have been shown to regulate activation of p38 MAPK by phosphorylating and activating MEK3 and 6. Little is known about the precise cellular roles for these TAO protein kinases, or whether they function together or individually within …

    utswmed Repository record for Identification of Intracellular Signaling Pathways Regulated by the TAO Family of Mammalian STE20p Kinases (opens in a new tab)