Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"MAOA"”.
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How MAOA, decision-making, and negative parenting impact aggression and conduct problems in children: a gene by environment interaction study
… moderates the relationship between MAOA gene variant and aggression/conduct problems and if low/high MAOA and negative parenting will moderate decision-making and aggression/conduct problems. Method: Study used archival baseline data from a population of at-risk children. Measures …
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Examining the MAOA gene and its potential role in the effect of childhood maltreatment on borderline personality traits and emotion dysregulation
… of the disorder and the gene mono oxidase A (MAOA). Specifically, a positive association was found between MAOA-H and the presence of BPD traits when childhood maltreatment was experienced. The current study sought to expand past research that used female participants because thus far research …
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The monoamine oxidase A gene as a potential moderator of the relationship between parental rearing and symptoms of borderline personality disorder in female undergraduates
… such as the Monoamine Oxidase A gene (MAOA). The present study pursued this line of investigation. Three variants of the MAOA gene were focused on. The highly active variant MAOA-H has been found in significantly higher rates among patients with Borderline Personality Disorder. The …
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The Social Environment, Genetics, and Obesity: Evaluation of Diathesis-Stress and Differential Susceptibility Frameworks
… Health study, the current study explores how the MAOA and 5-HTTLPR gene alleles interact with known predictors of obesity to compare and contrast the different frameworks. Results reveal that MAOA and 5-HTT do not have the same effect on obesity, especially when socioeconomic status and gender are …
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Antecedents of Borderline Personality Disorder and Antisocial Personality Disorder: An Examination of Gene X Environment Interactions
… emotionality, such as monoamine oxidase-a (MAOA), interact with negative early environmental factors like childhood maltreatment and develop into the disorders know as Borderline Personality Disorder (BPD) and Antisocial Personality Disorder (ASPD). Using existing data from a prospective …
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Polymorphisms in the COMT and MAOA genes and their consequences for clinical, neuropsychological and neuroimaging dimensions in a population at high risk of schizophrenia
… Dopamine is degraded by two enzymes COMT and MAOA. Thus mutations in the genes controlling the effectiveness of these enzymes may render subjects with a hyperdopaminergic state. This thesis will concentrate on two specific Single Nucleotide Polymorphisms in the MAOA and COMT genes and their …
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The effect of genotype on attention bias in rhesus macaques, Macaca mulatta, as a welfare indicator.
… short and long allele), monoamine oxidase A (MAOA; 5-, 6- and 7-repeat allele) and mu-opioid receptor (OPRM1; C and G allele). Additionally, sequencing was utilised to identify novel SNPs in the dopamine receptor D4 (DRD4). The 5-HTTLPR short-, TPH2 long-, MAOA 7-repeat and OPRM1 G-allele are …
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The Neurobiology of Reward Processing in Adolescence
… whether the X-linked gene Monoamine Oxidase A (MAOA) is associated with ventral striatal brain activation during reward anticipation and 4) to investigate whether MAOA stratifies the relationship between ventral striatal activation and ADHD symptoms in boys. Objectives 1 and 2 were explored …
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Born to Rage? : A Case Study of the Warrior Gene
… academic and popular media coverage of the MAOA-L gene variant, also known as the warrior gene, I outline the differences between academic and popular media. Furthermore, I analyze a television show: <italic>Born to Rage?<italic> and outline its coverage of controversial topics, use of field …
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Regulation von Adenosin- und Glutamatrezeptoren bei Mäusen mit molekularen Defekten des Serotoninsystems
… andererseits den Mangel an Monoaminoxidase A (MAOA). Dabei verglichen wir Mäuse mit einem einzelnen Knockout des entsprechenden Gens mit Doppelknockout-Tieren, denen beide Gene fehlten. Desweiteren untersuchten wir die Veränderung der Konzentration an Glutamatrezeptoren bei alten Tieren mit …
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Klonalitätsanalyse mittels PCR-Amplifikation X-chromosomal-gebundener Gene (MAOA und HUMARA) am Beispiel von Leiomyomen des Uterus und deren Anwendung auf das Krankheitsbild des benignen metastasierenden Leiomyoms zur Klärung dessen Pathogenese
… The chosen gene locus was that of the MAOA gene, which has already been useful for this PCR-analysis at lymphomas and hematopoietic cells of heterocygous women. This MAOA-assay was shown to be well suited for the clonality analysis of fresh frozen tissue. The thesis lists the pros and …
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Developmental Monoamine Signaling Impacts Adult Affective and Aggressive Behaviors
… transporter (5-HTT) and monoamine oxidase A (MAOA) blockade. Pharmacologic MAOA or 5-HTT blockade in adulthood has antidepressant and anxiolytic efficacy. Yet, genetically conferred MAOA or 5-HTT hypo-activity is associated with altered aggression and increased anxiety/depression. Here I test …
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A multipronged approach to understanding how genes contribute to social behavior in threespine stickleback
… of candidate genes, monoamine oxidase (MAOA) and arginine vasopressin (AVP), on territorial aggression in the sticklebacks. This method is flexible, fast, and amenable to statistically powerful within-subject experimental designs, making it practical for use in natural populations. Fish …
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Cortisol in Middle Childhood: Associations with Genetic Polymorphisms and Early Environmental Risk
… involving three polymorphisms (COMT Val158Met, MAOA-LPR, and 5-HTTLPR) has yielded well publicized but inconsistently replicated associations with mental health. Part of this inconsistency may be due to the limited exploration of mechanistic explanations for how these gene-environment …
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THE EFFCT OF LOW-LEVEL LEAD ON SEROTONIN EXPRESSION IN THE DEVELOPING MOUSE SUPERIOR OLIVARY COMPLEX AND SOMATOSENSORY CORTEX
… sections were immunostained for 5-HT, SERT, TPH, MAOA, VMAT2, SYP and GAP-43. Total brainstem levels of 5-HT and its metabolite 5-hydroxindole-3-acetic acid (5HIAA), were measured by HPLC. We found that Pb extends the normal developmental uptake of 5-HT by LSO neurons through prolonged expression …
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THE EFFCT OF LOW-LEVEL LEAD ON SEROTONIN EXPRESSION IN THE DEVELOPING MOUSE SUPERIOR OLIVARY COMPLEX AND SOMATOSENSORY CORTEX
… sections were immunostained for 5-HT, SERT, TPH, MAOA, VMAT2, SYP and GAP-43. Total brainstem levels of 5-HT and its metabolite 5-hydroxindole-3-acetic acid (5HIAA), were measured by HPLC. We found that Pb extends the normal developmental uptake of 5-HT by LSO neurons through prolonged expression …
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Dopaminergic Genetic Contributions to Obesity in Kidney Transplant Recipients
… rs4680 and rs4818, monoamine oxidase A gene (MAOA) VNTR, monoamine oxidase B gene (MAOB) SNP rs1799836, and dopamine active transporter gene (SLC6A3/DAT1) VNTR. Genotypes were analyzed using dose dependent and risk allele approaches, and those variants with p≤0.20 were included in regression …