Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"MAMPs"”.
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Elucidating three novel mechanisms of Pseudomonas syringae pathogenicity
… microbial-associated molecular patterns (MAMPs). Adapted pathovars of P. syringae secrete effector proteins through a Type Three Secretion System (T3SS) to suppress the immune response elicited by their MAMPs. However, secretion of effectors can also trigger a strong plant immune response …
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Plasticity of Adrenal Chromaffin Cell Function During Inflammation and Exposure to Microbe-Associated Molecular Patterns
… detect microbe-associated molecular patterns (MAMPs). Ca2+ signaling was assessed in single ACCs isolated from control mice and mice with GI or systemic inflammation using Ca2+ imaging and perforated patch clamp electrophysiology. Acute and chronic GI inflammation consistently reduced …
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Genomic characterizations of Xanthomonas cucurbitae and using comparative genomics to predict novel microbe-associated molecular patterns in Xanthomonas
… known microbe-associated molecular patterns (MAMPs), and we were able to characterize the recognition of these MAMPs between species in luminol-based reactive oxygen species (ROS) assays. While this study was not yet able to identify novel MAMPs, we show that Tajima’s D is a powerful tool in …
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Dissection of Innate Immunity in Tomato and Tolerance to Bacterial Wilt in Solanaceae species
… microbial-associated molecular patterns (MAMPs) and secreted pathogen proteins, called effectors. MAMP-triggered immunity (MTI) relies on recognition of MAMPs by leucine-rich repeats (LRRs) pattern-recognition receptors (PRRs). The best-studied LRR PRR is Flagellin-Sensitive 2 (Fls2), the …
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Bacterial outer membrane vesicles (OMVs) as a platform for personalized cancer vaccines
… several Microbe-Associated-Molecular Patterns (MAMPs), crucial for stimulating innate immunity and promoting adaptive immune responses. The ability to engineer OMVs with cancer epitopes together with their unique adjuvanticity and safety make them a particularly interesting vaccine platform. In …
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Analysis and optimization of immune responses elicited by Outer Membrane Vesicles (OMVs)
… many microbe-associated molecular patterns (MAMPs) such as peptidoglycan, lipopolysaccharide (LPS), and lipoproteins and can be decorated with foreign antigens. Thanks to these properties OMVs are becoming an attractive vaccine platform. However, a systematic investigation on the potentiality …
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Immunomodulatory effects exerted by Lactobacillus salivarius strains on innate immune cells
… recognize microbe-associated molecular patterns (MAMPs) and play a critical role in shaping microbial-specific innate and adaptive immune responses. Following ligand engagement, TLRs trigger a complex network of signalling that culminate in the production of inflammatory mediators. The …
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The impact of heptose phosphates on HIV latency and human immune responses
… class of microbe-associated molecular patterns (MAMPs) that is shed by N.gonorrhoeae to drive the modulation of an inflammatory response through the TIFA-dependent NF-κB signaling cascade. Here, I report that immunogenic heptose phosphates show promise as HIV latency reversal agents. Heptose …
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Functional Analysis of Plant Glutamate Receptors
… fungal microbe-associated molecular patterns (MAMPs) were diminished in seedlings treated with known agonists and antagonists of mammalian iGluRs, suggesting potential roles of GLRs in pathogen responses. Analysis of publicly available microarray data shows altered gene expression of a …
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Construction and characterization of proteome-minimized OMVs from E. coli and their exploitation in infectious disease and cancer vaccines
… several Microbe-Associated-Molecular Patterns (MAMPs), crucial for stimulating innate immunity and promoting adaptive immune responses. Second, they can be easily purified from the culture supernatant, thus making their production process inexpensive and scalable. Third, OMVs can be engineered …
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Regulating the stabilities of NOD1 and NOD2, two innate immune receptors, with sugars and chaperones
… to microbe associated molecular patterns (MAMPs) unique to specific microorganisms. Two well characterizes PRRs are nucleotide- binding oligomerization domain containing proteins 1 and 2 (NOD1 and NOD2), members of the NOD-like receptor family (NLRs). These NLRs recognize different …
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IDENTIFICATION OF COMMON MECHANISMS TO INTRACELLULARLY ACCOMMODATE BENEFICIAL OR PATHOGENIC FUNGI IN RICE
… of microbe-associated molecular patterns (MAMPs) by plasma membrane-bound receptors, which then activate cellular signalling pathways, leading to either immune responses or symbiosis. A key conceptual advance of this study is the identification of rice Chitin Elicitor Receptor Kinase 1 …