Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"MALT1"”.
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The Roles of Malt1 In Nf-Κb Activation and Solid Tumor Progression
… lymphoma translocation protein 1 (MALT1), also known as paracaspase, is required for EGFR-induced NF-κB activation by recruiting E3 ligase TRAF6 to the IKK complex. In addition, MALT1 also contributes to many malignant phenotypes, including tumor cell proliferation, survival, …
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De novo Design of Mini-Protein Binders Targeting Allosteric Sites of MALT1 Towards Cancer Therapeutics
Η MALT1 (Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1) αποτελεί βασικό ρυθμιστή της σηματοδότησης NF-κB, και η απορρύθμιση της δραστηριότητάς της εμπλέκεται σε ποικίλες αιματολογικές κακοήθειες και συμπαγείς όγκους, συμπεριλαμβανομένων του γλοιοβλαστώματος και του παγκρεατικού …
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Molecular Pathogenesis of MALT lymphoma
… is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway. Gastric MALT lymphomas harbouring such translocation do not respond to Helicobacter pylori eradication, while those without translocation …
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Etablierung stabiler Transfektanten für funktionelle Analysen des MALT1-Gens in t(11;18)(q21;q21)-positiven MALT-Typ-Lymphomen
Marginalzonen-B-Zell-Lymphome vom MALT-Typ stellen die häufigste Form primär extranodaler Non-Hodgkin-Lymphome dar. Sie entstehen auf dem Boden einer chronischen infektiösen oder autoimmunen Entzündung in hierdurch sekundär erworbenem lymphatischen Gewebe. Eine charakteristische und die häufigste …
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Genetic and molecular factors regulating growth and morphology in Senegalese sole (Solea senegalensis)
… groups 5 and 14 included the candidate genes malt1 and vtg3, also ubiquitous DETs, and the gen bmpr1b close to malt1, suggesting that inflammatory processes and BMP signaling pathways could contribute to modifying the axial skeleton and, consequently, the body ellipticity. Finally, this thesis …
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Carbon-13 metabolic flux analysis of soybean central carbon metabolism: response to temperature and genotype effects
… carboxylase (ppc) and the malate transporters (malT1 and malT2) between cytosol, mitochondrion and plastid varied considerably with temperature. The redirection of carbon between these cellular compartments had a direct influence on the carbon partitioning into protein and oil from the plastidic …