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Showing 1 to 20 of 133 for “"MALDI-TOF MS"”.
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MALDI-TOF MS Data Processing Using Wavelets, Splines and Clustering Techniques.
… matrix assisted laser desorption/ionization (MALDI) time of flight (TOF), is emerging as a leading technique in the proteomics revolution. It can be used to find disease-related protein patterns in mixtures of proteins derived from easily obtained samples. In this paper, a novel algorithm for …
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Characterization of A-type Proanthocyanidins in Peanut Skins Using MALDI-TOF MS
… ionization-time of flight mass spectrometry (MALDI-TOF MS). Many similarities were found in the proanthocyanidin composition of cranberries and peanut skins. New oligomeric and polymeric proanthocyanidins in peanut skins, including heteroproanthocyanidins and proanthocyanidins with sugar …
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Rapid methods for bacterial identification and predicting antibiotic resistance by MALDI-TOF MS
… ionization time-of-flight mass spectrometry (MALDI-TOF MS) as a high throughput, cost-effective alternative to conventional methods in clinical diagnostics has been the basis for a large portion of these. Current techniques for routine bacterial identification involve culture-, biochemical-, …
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Modification of substrate specificity of thioesterase, reductase, desaturase by MALDI-tof-MS analysis of microbial colonies
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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Caracterización fenotípica y proteómica (MALDI-TOF MS) de bacilos Gram negativos multireesistentes aislados en un Hospital Universitario Chileno
… clínica. La espectrometría de masas MALDI-TOF es una herramienta que ha revolucionado el diagnóstico microbiológico. La gran especificidad de los espectros obtenidos, la rapidez con que se obtienen resultados y su relativamente bajo costo por muestra analizada han hecho de MALDI-TOF …
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Integrating Micro-Scale Separations to Matrix Assisted Laser Desorption and Ioniation Time of Flight Mass Spectrometry (MALDI-TOF-MS) for Protein Analysis
… and ionization time-of-flight mass spectrometry (MALDI TOF MS) for protein analysis. MALDI MS provides unsurpassed accurate mass measurements of intact bio-molecules, for example peptides and proteins, which in turn generate high molecular specificity enabling the identity, function and structure …
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GLYCOPEPTIDE ANALYSIS OF HIV-1 ENVELOPE PROTEIN USING HPLC/ESI-FTICR MS AND MALDI-TOF MS WITH ASIALOFETUIN ENRICHMENT AND SEPARATION TECHNIQUES
… of the glycans as well as their various glycoforms makes glycans unique to analyze due to the fact that the variation in structure is not based on a genomic code. Glycosylation is a post-translational modification that provides diverse glycoforms. Mass spectrometry has become a standard technique …
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Identification of Anaerobes in Clinical Specimens Comparison between the RapID ANA II System and the Bruker MALDI-TOF MS System utilized in the Clinical Laboratory
… and Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has been revealed as an invaluable platform for identifying anaerobic bacteria in the clinical laboratory over traditional methods such as the RapID ANA II System.</p> <p>A qualitative comparison is made, through the analysis of …
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Rapid and high-resolution analysis of winemaking yeasts using MALDI-TOF MS : A thesis submitted in partial fulfilment of the requirements for the Degree of Doctor of Philosophy at Lincoln University
… ionization-time of flight mass spectrometry (MALDI-TOF MS) has been successfully applied to identify yeast species relevant to winemaking. This technology has shown potential in the prediction of the utility of individual yeast strains in the production of different wine styles. Despite this …
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The Synthesis and Study of Dendrimers and Star Polymers Without Cores
… cross-linked. The combined use of MALDI-TOF MS and SEC analysis of the resulting structures indicated that in each case, as the degree of dendrimer cross-linking increased, its radius of gyration (Rg) decreased linearly. Upon cross-linking of the dendrimer having 64 alkene groups, …
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Modifizierte Peptidnucleinsäuren für die sequenzselektive DNA-Spaltung und DNA-Nachweis
… Metallkatalyse. Im ersten Projekt konnte durch MALDI-TOF MS und HPLC der Zr(IV)-Komplex des Tris(hydroxymethyl)-aminomethan-PNA-Konjugats (Zr(IV)-15) als aktivste Spezies zur Spaltung komplementärer DNA identifiziert werden. Die Spaltung der Ziel-DNA erfolgte sequenzselektiv zu 91% (nach 164 …
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Pilot study: identification of anthocyanin metabolites in the mice fed purple-fleshed sweetpotato
… analyzed for anthocyanin metabolites using HPLC/MS and MALDI-TOF-MS. Fifteen hours after consumption of P40 diet, we identified 4 anthocyanin metabolites cyanidin 3,5- diglucoside; cyanidin 3-sophoroside-5-glucoside; cyanidin3-p-hydroxybenzoylsophroside-5-glucoside; and peonidin …
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Structure-Function Relationships in Poly(3-hexylthiophene)s Formed via Manipulation of Oxidative Coupling Routes
… time-of-flight mass spectrometry (MALDI-ToF-MS) was used to characterize the endgroup additions to and obtain molecular weight data about poly(3-hexylthiophene) formed using different experimental conditions. The regioregularity of the materials was evaluated by means of 1H-NMR. …
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Analysis and characterisation of human chorionic gonadotropin glycoforms in pregnancy and trophoblastic disorders
… ionisation time of flight mass spectrometry (MALDI-TOF MS). hCG isolated from pooled pregnancy urine was used in this study. All the stages in pregnancy urine preparation were optimised; including conditions for hCG immunopurification, deglycosylation, solid-phase extraction of resulting …
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Peptide Analysis Using Capillary Electrophoresis With Fluorescence Detection
… ionization time of flight mass spectrometry (MALDI-TOF MS) for the identification of unknown peptides.
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Diagnostic characterization of Malassezia pachydermatis isolates from canine otitis externa
… ionization time-of-flight mass spectrometry (MALDI-ToF MS) identification was used, and common biochemical assays were conducted. A subset of isolates could not be identified using the MALDI-ToF MS standard library and had different colony morphologies than the M. pachydermatis type strain, …
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The proteomic analysis of resistance to anticancer therapy in human breast cancer
… our understanding of the resistance mechanisms and may allow therapy to be tailored on an individual patient basis. Those patients unlikely to respond to a particular treatment strategy would be spared the serious life-threatening side effects for no therapeutic gain. The immediate …
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Διαγνωστικές μέθοδοι σύγχρονοι και κλασσικότεροι προσέγγισης των ονυχομυκητιάσεων
… οι νεότερες τεχνικές, όπως PCR και παράγωγά της, MALDI-TOF MS, ονυχοσκόπηση, OCT , RCM κα. Αποτελέσματα: Οι κλασικές μέθοδοι παραμένουν θεμελιώδεις λόγω χαμηλού κόστους και ευρείας διαθεσιμότητας, ωστόσο παρουσιάζουν περιορισμούς στην ευαισθησία, στην ταχύτητα και στην ικανότητα ταυτοποίησης. Οι …
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Development of Assays for Neuronal Peptide Content and Release
Neuropeptide release is also studied with MALDI TOF MS. In this method, a small chamber (10 $\mu$l) is used to hold an isolated bag cell cluster in a small volume of physiological saline. The chamber consists of a standard pipette tip with the narrow end melted around two sections of fused silica …
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The cardioprotective mechanisms of dietary flavonoids
… cardiomyocyte to study the protective mechanisms of dietary flavonoids, but they lack features of fully differentiated cardiomyocytes. Therefore, this present study aimed to investigate the cytoprotective and cytotoxic effects of the dietary flavonoids quercetin, kaempferol, myricetin and two …
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