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Showing 1 to 20 of 297 for “"MALDI-TOF"”.
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Characterization of Oligosaccharides and Nanoparticles by MALDI-TOF Mass Spectrometry
… of small oligosaccharides by negative ion mode MALDI using anion attachment followed by PSD are investigated. By careful initial adjustment of the focusing mirror ratios allowing acquisition of the peaks of interest within the same PSD segment, it is possible to obtain highly reproducible …
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MALDI-TOF MS Data Processing Using Wavelets, Splines and Clustering Techniques.
… matrix assisted laser desorption/ionization (MALDI) time of flight (TOF), is emerging as a leading technique in the proteomics revolution. It can be used to find disease-related protein patterns in mixtures of proteins derived from easily obtained samples. In this paper, a novel algorithm for …
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Gold compact disc appended Tröger’s base scaffolds as MALDI-TOF biodetection probes
… detection of these biological interactions via MALDI-TOF spectrometry will be probed. The (+)-biotin / streptavidin interaction will be used as a model study for these purposes with the ambition to develop this further with humanitarian and military applications. The V-shape and 90˚ angle of …
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Characterization of A-type Proanthocyanidins in Peanut Skins Using MALDI-TOF MS
… ionization-time of flight mass spectrometry (MALDI-TOF MS). Many similarities were found in the proanthocyanidin composition of cranberries and peanut skins. New oligomeric and polymeric proanthocyanidins in peanut skins, including heteroproanthocyanidins and proanthocyanidins with sugar …
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Rapid methods for bacterial identification and predicting antibiotic resistance by MALDI-TOF MS
… ionization time-of-flight mass spectrometry (MALDI-TOF MS) as a high throughput, cost-effective alternative to conventional methods in clinical diagnostics has been the basis for a large portion of these. Current techniques for routine bacterial identification involve culture-, biochemical-, …
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Modification of substrate specificity of thioesterase, reductase, desaturase by MALDI-tof-MS analysis of microbial colonies
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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Optimizing main spectrum profiles for use in real-time MALDI-TOF mass spectrometry identification of Leptospira serovars
… Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) by diagnostic laboratories for microorganism identification to the species-level, MALDI-TOF MS was explored as a potential method for serovar detection and identification in leptospirosis-positive canine urine samples. Commercial MALDI …
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Caracterización fenotípica y proteómica (MALDI-TOF MS) de bacilos Gram negativos multireesistentes aislados en un Hospital Universitario Chileno
… clínica. La espectrometría de masas MALDI-TOF es una herramienta que ha revolucionado el diagnóstico microbiológico. La gran especificidad de los espectros obtenidos, la rapidez con que se obtienen resultados y su relativamente bajo costo por muestra analizada han hecho de MALDI-TOF …
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Integrating Micro-Scale Separations to Matrix Assisted Laser Desorption and Ioniation Time of Flight Mass Spectrometry (MALDI-TOF-MS) for Protein Analysis
… and ionization time-of-flight mass spectrometry (MALDI TOF MS) for protein analysis. MALDI MS provides unsurpassed accurate mass measurements of intact bio-molecules, for example peptides and proteins, which in turn generate high molecular specificity enabling the identity, function and structure …
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GLYCOPEPTIDE ANALYSIS OF HIV-1 ENVELOPE PROTEIN USING HPLC/ESI-FTICR MS AND MALDI-TOF MS WITH ASIALOFETUIN ENRICHMENT AND SEPARATION TECHNIQUES
Glycosylation on proteins serve many biological roles and their heterogeneity can affect various biological functions. The site occupancy of the glycans as well as their various glycoforms makes glycans unique to analyze due to the fact that the variation in structure is not based on a genomic …
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Identification of Anaerobes in Clinical Specimens Comparison between the RapID ANA II System and the Bruker MALDI-TOF MS System utilized in the Clinical Laboratory
… and Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has been revealed as an invaluable platform for identifying anaerobic bacteria in the clinical laboratory over traditional methods such as the RapID ANA II System.</p> <p>A qualitative comparison is made, through the analysis of …
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Rapid and high-resolution analysis of winemaking yeasts using MALDI-TOF MS : A thesis submitted in partial fulfilment of the requirements for the Degree of Doctor of Philosophy at Lincoln University
… ionization-time of flight mass spectrometry (MALDI-TOF MS) has been successfully applied to identify yeast species relevant to winemaking. This technology has shown potential in the prediction of the utility of individual yeast strains in the production of different wine styles. Despite this …
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Proteomic comparison of Amoxicillin resistant and susceptible periodontal Provotella Intermedia and Provotella Nigrescens clinical isolation with Matrix-Assisted Laser Disportion Ionization Time-Of-/flight mass spectrometry
… laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry, and associated analytic software for the definitive identification P. intermedia and P. nigrescens in clinical specimens, has been approved for clinical microbiology diagnostic use in the United States by the Food and …
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The Synthesis and Study of Dendrimers and Star Polymers Without Cores
… cross-linked. The combined use of MALDI-TOF MS and SEC analysis of the resulting structures indicated that in each case, as the degree of dendrimer cross-linking increased, its radius of gyration (Rg) decreased linearly. Upon cross-linking of the dendrimer having 64 alkene groups, …
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Post-translational modifications of SEL24K from salmon eggs and ZPA from Xenopus laevis eggs
… digestion strategy in combination with MALDI-TOF mass spectrometry analysis. The disulfide bond pattern was found to be symmetrical in the tandem repeat sequence of SEL24K. More importantly, an interesting phenomenon of gas-phase scrambling of disulfide bonds was observed during MALDI …
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Modifizierte Peptidnucleinsäuren für die sequenzselektive DNA-Spaltung und DNA-Nachweis
… Metallkatalyse. Im ersten Projekt konnte durch MALDI-TOF MS und HPLC der Zr(IV)-Komplex des Tris(hydroxymethyl)-aminomethan-PNA-Konjugats (Zr(IV)-15) als aktivste Spezies zur Spaltung komplementärer DNA identifiziert werden. Die Spaltung der Ziel-DNA erfolgte sequenzselektiv zu 91% (nach 164 …
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Diagnostic characterization of Malassezia pachydermatis isolates from canine otitis externa
… ionization time-of-flight mass spectrometry (MALDI-ToF MS) identification was used, and common biochemical assays were conducted. A subset of isolates could not be identified using the MALDI-ToF MS standard library and had different colony morphologies than the M. pachydermatis type strain, …
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Pilot study: identification of anthocyanin metabolites in the mice fed purple-fleshed sweetpotato
… for anthocyanin metabolites using HPLC/MS and MALDI-TOF-MS. Fifteen hours after consumption of P40 diet, we identified 4 anthocyanin metabolites cyanidin 3,5- diglucoside; cyanidin 3-sophoroside-5-glucoside; cyanidin3-p-hydroxybenzoylsophroside-5-glucoside; and peonidin …
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Structure-Function Relationships in Poly(3-hexylthiophene)s Formed via Manipulation of Oxidative Coupling Routes
… time-of-flight mass spectrometry (MALDI-ToF-MS) was used to characterize the endgroup additions to and obtain molecular weight data about poly(3-hexylthiophene) formed using different experimental conditions. The regioregularity of the materials was evaluated by means of 1H-NMR. …
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Structure-Function Relationship Studies of the Cytochrome Oxidases
… anhydrase standard (molecular weight 36800). MALDI-TOF mass spectrometry analysis identified this as a single peak with a m/z of 34336.4, which is exactly twice the mass of subunit IV. It is believed that a covalent linkage of subunit IV is made.
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