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Showing 1 to 1 of 1 for “"M2R-GIRK signaling"”.
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GPCR to Channel Communication in a Membrane Signaling Pathway
… contrast, activation of M2 muscarinic receptors (M2Rs) and the inhibitory G protein (Gαi) opens G protein-gated inward rectifier K⁺ (GIRK) channels, slowing the heart rate. In addition to the Gαs and Gαi pathways, there is also the Gαq signaling pathway. In this pathway, activation of Gq-coupled …