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Showing 1 to 1 of 1 for “"M1 ubiquitin"”.

  1. An investigation into the role of LUBAC and linear ubiquitin chains in antibody dependent intracellular neutralisation

    … It requires TRIM21, an Fc receptor and E3 ubiquitin ligase that resides in the cytosol. Binding of TRIM21 to the exposed Fc portion of an antibody that is bound to an internalised virus results in ubiquitin signalling and proteasomal degradation of the virus. Viruses are large, complex …

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