Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 46 for “"M1 M2"”.
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Macrophage Polarization (M1/M2) and its Role in Wnt5a Secretion/Expression in Atherosclerosis
… lesions and their progression. The presence of M1 and M2 macrophages in human atherosclerotic lesions has been suggested. Wnt5a is a noncanonical member of the wingless family of proteins that is expressed in human macrophages in different inflammatory diseases including atherosclerosis. These …
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REGENERATION OF ELECTROSPUN BIORESORBABLE VASCULAR GRAFTS: A PHENOMENON ASSOCIATED WITH VASCULAR GRAFT PROPERTIES AND MACROPHAGE PHENOTYPES (M1/M2)
… plasticity and can acquire pro-inflammatory (M1) or angiogenic/wound healing (M2) phenotypes depending upon the environmental stimuli. The phenotypic profile of MФ as M1 or M2 following exposure to the biomaterial can dictate the downstream processes of tissue remodeling and angiogenesis. An …
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Charakterisierung von Monozyten anhand ihrer Interleukin-10-Produktion und Darstellund der Existenz funktionell unterschiedlicher Subpopulationen (M1/M2) analog den Th1/Th2-Schema
… Monozyten-Subpopulationen existieren, die als M1-Monozyten (entsprechend klassisch aktivierten Makrophagen) und M2-Monozyten (entsprechend alternativ aktivierten Makrophagen) bezeichnet werden können.
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Identification of macrophage phenotypes and evaluation of their role in the immunopathogenesis in animal model of Behçet’s disease
… heterogeneous and include classically activated (M1) and alternatively activated (M2) macrophages. In a herpes simplex virus (HSV)-induced BD mouse model, it has confirmed the abundant expression of the M1 phenotype (CD16/32) compared to the M2 phenotype(CD23). For M1/M2 phenotypic transformation …
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Prediction of In-Vivo Antimuscarinic Activity (AMA) by In-Vitro Receptor Binding Assessment and PK/PD Modeling For Prototypical Drugs
… using 3H-QNB and membrane suspensions of M1, M2, and M3. Cmax, values were combined with Ki values to generate the relevant AMA. Validation of the AMA biomarker was carried-out against the reported AMAEs incidence. Results: With the exclusion of scopolamine and olanzapine for CNS and …
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Quantifying changes in accelerations and heart rate indicative of fatigue during condensed competitions in elite youth ice hockey players
… point across G1–G4 and multiple games per day (M1, M2) for magnitude and time as main effects were performed. HR beats per minute decreased between G1 and G3/G4 in time segments (3–20 minutes) although ACC were not different. Peak ACC were lower for M2 vs M1 at 60, 90, 120 and 180 seconds. …
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An Investigation into the Effects of Macrophage Polarisation on Interleukin-1 Expression
… into two opposing subtypes: the pro-inflammatory M1 and anti-inflammatory M2 macrophages. Macrophages are also the main cell type that produces two powerful cytokines that drive chronic inflammation and adaptive immunity - interleukin (IL)-1α and IL-1β. Although the role of M1 macrophages as …
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Relationship of Water Intake and Cognitive Function, Communication/Hearing, and Vision Pattern Among Nursing Home Residents
… exceeded 100% the standard requirement of 1,600 m1/m2 of body surface area; 14 met or exceeded 66% of their requirement. Variables significantly found to be associated with inadequate water intake were increased length of stay, inability to recall current season, and hearing difficulty. Health …
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Pembangunan elemen multimedia berasaskan content dan context seni untuk pendidikan latihan teknikal dan vokasional
… Delphi Method untuk mendapatkan nilai purata m1, m2 dan m3, nilai ‘d’ Threshold value, konsensus 75% pengesahan kumpulan pakar dan Fuzzy Evaluation. Dapatan bagi Fasa pertama 80 item daripada 8 elemen namun di dalam elemen deria mempunyai tiga item yang telah ditolak namun peratusan …
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Pembangunan elemen multimedia berasaskan content dan context seni dalam PdP untuk pendidikan latihan teknikal dan vokasional
… Delphi Method untuk mendapatkan nilai purata m1, m2 dan m3, nilai ‘d’ Threshold value, konsensus 75% pengesahan kumpulan pakar dan Fuzzy Evaluation. Dapatan bagi Fasa pertama 80 item daripada 8 elemen namun di dalam elemen deria mempunyai tiga item yang telah ditolak namun peratusan …
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Protein Biomarkers of Ionizing Radiation and Standardization by MALDI MS/MS and Quantification
… (down-regulated), pyruvate kinase isozymes M1/M2 (down-regulated) and ATP synthase subunit beta, mitochondrial precursor (down-regulated).
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Enhancing Anti-Cancer Immunotherapy by Disruption of the non-Receptor Tyrosine Kinase Fes
… were associated with enhanced in vivo ratios of M1/M2 tumour associated macrophages, as well as activation of and PD-1 expression on tumour associated T cells. In vitro, Fes-deficient bone marrow derived macrophages demonstrated an increase in Toll-like receptor signaling in antigen presenting …
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Bottleneck-based heuristic for permutation flowshop scheduling
… There are four potential dominant machines (M1, M2, M3, M4) clustered as bottleneck machines. A total 1000 set random processing time for each job sizes was tested using Excel simple programming with built in Visual Basic for Application (VBA). The heuristic performance was evaluated based on …
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Model-independent approaches to QCD and B decays
… classify AQCD/mb corrections to non-leptonic B - M1 M2 decays, where M1,2 are charmless mesons (flavor singlets excluded). The leading contributions to annihilation amplitudes as well as the leading "chirally enhanced" contributions are calculated and depend on twist-2 two-parton and twist-3 …
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First principles phase diagram calculations in group IV carbides and Mg2SiO4 liquid from Molecular Dynamics
… large number of supercells with compositions of (M1,M2)C, M1, M2 = Ti, Zr, or Hf, are computed by a plane-wave pseudopotential method. The energies serve as a basis for fitting cluster expansion Hamiltonians that are used to explore the sub-solidus phase diagram, i.e. stability of ordered …
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Aberrante DNA-Methylierung des Transkriptionsfaktors C/EBP[alpha] bei akuter myeloischer Leukämie
… in the French-American-British (FAB)-subtypes M1, M2, M4, M4eo und M5. Moreover hypermethylation was detected exclusively in cytogenetically favorable and intermediate risk groups. Clinical trials with demethylating agents as 5-aza-2’-desoxycytidine (DAC) und 5-azacytidin (AZA) provided …
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PHYSICOCHEMICAL STUDIES ON THE CATALYTIC AND REGULATORY SUBUNITS OF RIBONUCLEOTIDE REDUCTASE FROM CALF THYMUS
<p>The catalytic (M2) and regulatory (M1) subunits of calf thymus ribnucleotide reductase have been purified to homogeneity. Each runs as a single band in SDS-polyacrylamide gel electrophoresis with polypeptide molecular weights of 84,000 for M1 and 58,000 for M2. Additional evidence for …
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Some generalizations of injectivity
… Noetherian ring R, an extending right R-module M1 and a semisimple right R-module M2, the right R-module M1 M2 is extending if and only if M2 is M1/Soc(M1)-injective. Chapter 3 deals with the class of self-c-injective modules, that can be characterised by the lifting of homomorphisms from closed …
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Shallow Water Wave Propagation in Open Channel Flow
… are derived for each wave approximation in the M1, M2 and S1 type flow regimes. In the nonlinear wave analysis, a uniformly valid asymptotic nonlinear description of the wave in a rectangular channel is derived, at and away from the wave shock, as well as near the downstream boundary where the …
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Engineering the tumor microenvironment using microfluidics : effects of cell-cell interactions and endothelial barrier function on tumor cell intravasation
… of macrophage secreted factors and M1/M2 polarization status, identified that blocking macrophage-secreted TNF-a restored endothelial permeability and reduced tumor cell intravasation. In agreement with these results, we also found that the number and dynamics of tumor-endothelial …
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