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Showing 1 to 20 of 37 for “"M. avium"”.
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Epidemiology of <i>Mycobacterium avium</i> complex infecting AIDS patients
Organisms of the <i>Mycobacterium avium</i> complex cause disseminated infections in 25 to 50 % of patients with AIDS. To assess the likelihood of exposure to M avium, we attempted to recover M. avium complex from environmental samples in geographical areas (Boston, Massachusetts; Hanover, New …
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Disinfectant Susceptibility of Mycobacterium avium
Mycobacterium avium, an opportunistic human pathogen, infects between 25 and 50% of advanced-stage acquired immuno-deficiency syndrome (AIDS) patients in the United States. M. avium has been isolated from many environmental sources including: natural waters, soils, and aerosols. M. avium has also …
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Nitrate- and Nitrite-Reductase Activities in Mycobacterium Avium A5
Mycobacterium avium is human and animal opportunistic pathogen responsible for disseminated disease in immunocompromised patients. Mycobacteria have a capacity to adapt to the environmental conditions by inducing enzyme activities and altering their metabolism. M. avium A5 cells were grown in a …
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Analysing M. avium-macrophage interactions and establishing a long-term infection in a novel and realistic model of lung alveolar macrophages, Max Planck Institute Cells
Mycobacterium avium Complex (MAC) are species of the non-tuberculous branch of the Mycobacteria family that is responsible for the development of pulmonary lung disease in immunocompromised individuals. One of the first lines of defence from the host involve a specialised group of tissue …
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Rapid, Quantitative Assessment of Antimycobacterial Water Disinfection based on the Firefly Luciferase Reporter Gene
Mycobacterium avium causes disseminated infection in humans with immunodeficiency, pulmonary infections in individuals with predisposing lung conditions (e.g., pneumoconiosis), and cervical lymphadenitis in children. Twenty-five to fifty percent of late stage AIDS patients are infected with M. …
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Investigation of the host-mediated proteolytic response to pulmonary Mycobacterium Avium Complex infection
… is increasing rapidly. In the UK, Mycobacterium avium complex (MAC) is the most common pulmonary NTM infection outside the setting of cystic fibrosis lung disease. Patients with pulmonary MAC infection develop cavitating lung disease or nodular bronchiectasis. Prolonged treatment is required, …
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Investigation of catalase and superoxide dismutase from Mycobacterium avium, M. intracellulare and M. scrofulaceum
… detected in cell-free extracts of Mycobacterium avium, M. intracellulare and M. scrofulaceum (MAIS). The M. scrofulaceum isolates had the highest catalase activity, while both M. avium and M. intracellulare had significantly lower activities. The percentage of catalase activity remaining, after …
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Effect of growth in biofilms upon antibiotic and chlorine susceptibility of Mycobacterium avium and Mycobacterium intracellulare
Mycobacterium avium and Mycobacterium intracellulare are environmental opportunistic pathogens whose source for human infection is water and soil. M. avium and M. intracellulare cause pulmonary infections (tuberculosis) in immunocompetent individuals and bacteremia in immunodeficient individuals …
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Deciphering the molecular basis of the global emergence of non-tuberculous Mycobacteria as important human respiratory pathogens
Mycobacterium avium belongs to the group Nontuberculous Mycobacterium (NTM), which are acid fast, environmental bacteria belonging to the family Mycobacteriaceae. They are facultative intracellular bacilli causing opportunistic infections in individuals with pre-existing conditions such as …
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Macrolide Resistance in Mycobacterium avium
Mycobacterium avium isolates resistant to clarithromycin and azithromycin have been recovered from patients undergoing antibiotic therapy. Comparison of DNA fingerprints of sensitive and resistant isolates showed that resistance resulted from mutation of the original, sensitive isolate in five of …
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Critical factors controlling regrowth of opportunistic pathogens in premise plumbing
… (e.g., Legionella pneumophila, Mycobacterium avium complex, Acanthamoeba polyphaga, Pseudomonas aeruginosa) residing in human-made water systems, particularly premise plumbing, are now the primary source of water-borne disease in developed countries. The prevention and control of opportunistic …
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Development of Drug Loaded Nanoparticles for Treatment of Mycobacterium avium Infection
… of antimicrobial loaded nanoparticles against M. avium. Various in vitro efficacy studies were done with a) amikacin-loaded nanoparticles, b) clarithromycin-loaded nanoparticles, and c) with aerogel nanoparticles loaded with rifampicin, clarithromycin and ethambutol. Clarithromycin (CLA) and …
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Action of clofazimine on Mycobacterium avium and Mycobacterium intracellulare
… against a variety of mycobacteria including M. avium. The presence of clofazimine in growth medium resulted in higher carotenoid pigmentation in M. avium cells. Carotenoid pigments have been shown to quench superoxide radicals supporting the hypothesis that pigmentation possibly protected cells …
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Survival strategies of Mycobacterium avium subsp. paratuberculosis in a variety of microenvironments.
Mycobacteria, specifically Mycobacterium avium subsp. paratuberculosis (MAP), are extreme strategists and as a rule live by deception. Mycobacteria represent a group of closely related acid-fast bacilli that encompass a wide-range of host tropisms and diseases. Mycobacteria can be divided into two …
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Phylogenetic Analysis of the Mycobacteria and Diagnosis of Paratuberculosis by 16SrRNA Amplification and Probing
… with emphasis on members of the Mycobacterium avium-complex (MAC). All mycobacteria examined formed a closely related (average similarity $>$95%) and exclusive assemblage. Growth rate, thermotolerance, and virulence were shown to be phylogenetically restricted traits. The slow-growers formed a …
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Micobacterias atípicas identificadas en Asturias (2005-2012). Evaluación del método de gradiente antibiótico Etest para la realización de las pruebas de sensibilidad
… 212 pacientes (17,1%), siendo M. kansasii y M. avium fueron las especies que más a menudo se relacionaron con patogenicidad (67%). M. kansasii predominaba en hombres (p<0,01). Las MA en su mayoría se aislaron del tracto respiratorio (91,4%), siendo el esputo la muestra más frecuente. En muestras …
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Adherence and Biofilm Formation of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium abscessus in household plumbing
… factors. Three species of NTM, Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium abscessus, were examined for adherence and biofilm formation on surfaces common to household plumbing systems, including glass, copper, stainless steel, polyvinyl chloride, and galvanized steel. …
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Identifying cross-species regimens for the treatment of rapid-growing and slow-growing nontuberculous Mycobacterium pulmonary infections
… mycobacteria (NTM), especially Mycobacterium avium and Mycobacterium abscessus, are increasingly significant causes of chronic pulmonary disease. Current treatments are lengthy and often ineffective, with culture conversion often below 60% in refractory patient populations. Due to the close …
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Molecular Typing Of Mycobacterial Isolates Cultured From The Tissue Of Inflammatory Bowel Disease (Crohn's Disease) Patients
The role of Mycobacterium avium subsp paratuberculosis (MAP) in the etiology and pathogenesis of inflammatory bowel disease (IBD) including Crohn's Disease (CD), has been investigated. The fastidious characteristics and cross reactivity of MAP with other members in Mycobacteria have produced …
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Syntéza a hodnocení potenciálních antimykobakteriálních látek odvozených od hydrazinu
… high activity against non-tuberculous M. avium (MIC of 16-32 μM). Four molecules from the second series even exhibit some activity against MDR- TB and XDR-TB strains.
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