Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"M-DNA"”.
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A structural study of M-DNA
In alkaline conditions, a complex called M-DNA is formed between a divalent metal ion, cobalt, nickel or zinc, and duplex DNA. The rate of formation and stability of M-DNA is dependent on many factors, including but not limited to temperature, pH, DNA sequence, and metal or DNA concentrations. It …
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Localization of metal ions in DNA
M-DNA is a novel complex formed between DNA and transition metal ions under alkaline conditions. The unique properties of M-DNA were manipulated in order to rationally place metal ions at specific regions within a double-stranded DNA helix. Investigations using thermal denaturation profiles and the …
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Development & Application of Fluorescence Spectroscopy & Fluorescence Lifetime Imaging to Biology & Medicine
… of the structural properties of a metal-DNA complex (M-DNA); development and characterization of a genetically encoded biosensor for monitoring intracellular redox potentials; image analysis for FLIM; and, a microfluidic mixing device for accessing microsecond reaction kinetics.
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Development &Amp; Application of Fluorescence Spectroscopy &Amp; Fluorescence Lifetime Imaging to Biology &Amp; Medicine
… of the structural properties of a metal-DNA complex (M-DNA); development and characterization of a genetically encoded biosensor for monitoring intracellular redox potentials; image analysis for FLIM; and, a microfluidic mixing device for accessing microsecond reaction kinetics.
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Comparative Studies of Processivity Clamp Loader ATP Site Function
<p>DNA replicases utilize ring-shaped sliding clamps to ensure polymerase processivity. An ATP-dependent clamp loader topologically links the clamp around DNA in a multi-step mechanism. Clamp loaders are ring-shaped pentamers of AAA+ subunits. The pentamer complex contains 3-4 ATP sites, each …
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The Influence of DNA Methylation on Both H2A.Z Nucleosome Dynamics and the Zinc Finger and Homeoboxes Transcription Factor Family
<p>DNA methylation represents a widespread and heritable modification that exerts substantial influence on chromatin organization and function in many eukaryotic genomes. The presence of DNA methylation has been strongly linked to transcriptional regulation, in both activating as well as repressive …