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Showing 1 to 1 of 1 for “"M Phase Cell Cycle Checkpoints"”.
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The Multifunctional Kinase Bub1 Acts as a Signaling Hub for the Spindle Checkpoint
… sister chromatids and the progression from metaphase to anaphase requires the activation of an ubiquitin E3 ligase, anaphase-promoting complex or cyclosome (APC/C). Cdc20 is the mitosis-specific APC/C activator. The spindle checkpoint prevents premature sister chromatids separation by preventing …