Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Lytic phage"”.
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Elucidation of an oral drug delivery mechanism to the mammalian gastrointestinal tract via an engineered T4 phage
… we outline the potential to use bacteriophage as an alternative chassis for biologic production and delivery to the gastrointestinal tract, targeting and reducing symptoms of obesity and ulcerative colitis. Elucidation of this system presents a universal platform for the long-term …
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Isolation and Characterization of Bacteriophages from Fish tank Samples
<p>Bacteriophages (phages) are viral obligate intracellular parasites that infect bacteria. Research has been carried out on alternative treatment plans for bacterial infections due to the increase in antibiotic resistance. Phages have been proposed as an alternative to antibiotics. This research …
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Understanding and exploiting bacteriophage-host interactions for the control and detection of listeria monocytogenes
The hypothesis of this thesis is that phages isolated from the environment can play a role in the future to reduce outbreaks of the disease listeriosis by applying phages as biocontrol agents against the pathogen L. monocytogenes and by incorporating phages into systems for the detection of this …
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Adaptive Mechanisms of an Estuarine Synechococcus based on Genomics, Transcriptomics, and Proteomics
… GI genes occurred after CB0101 was infected by a lytic phage. On the other hand, phage-encoded host-like proteins (hli, psbA, ThyX) were highly expressed upon phage infection. This research provides new evidence that estuarine Synechococcus like CB0101 have inherited unique genetic machinery, …
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The role of physical interactions in shaping the genetic diversity of spatially expanding phage and bacterial populations
… First, I examine viral-host dynamics in bacteriophages, viruses that infect bacteria. Second, I explore the impact of phenotypic heterogeneity within B. subtilis biofilms during expansions on solid-air interfaces. I consider the scenario of a lytic phage which replicates by infecting a lawn of …
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Biological Consequences of Atypical Phage Conversion in Gram-Positive Pathogens
<p>Temperate bacteriophage have a complex, dynamic relationship with bacteria: parasitizing in the lytic cycle, but often increasing bacteria's fitness as lysogens. The phage-bacteria relationship is vast and has evolved over more than an estimated three billion years, and there are likely many …
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Isolation, Characterisation and Preservation of Bacteriophages for Use in Treatment of Aeromonas hydrophila Infection In Finfish
… infections in the aquaculture sector. Bacteriophages (phages) demonstrated promising results as therapeutic tools, for the effective control of bacterial diseases in aquaculture, as well as in other production animals, companion animals and humans. In the present study, a range of …